Page 433 - Veterinary Immunology, 10th Edition
P. 433

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                            FIG. 15.1  The overall structure of an immunoglobulin molecule.
                              When expressed on a B cell surface, this molecule acts as an
                           antigen receptor (BCR). When released by the B cell and free in the
                           circulation, it acts as an antibody. Note that unlike a TCR, it has two
                                                  antigen-binding sites.

























                            FIG. 15.2  The effect of treating an immunoglobulin molecule with
                              the proteolytic enzyme papain. The names of these fragments
                            denote the nomenclature of different regions of an immunoglobulin
                                molecule. Fab, Fragment-antibody binding; Fc, Fragment
                                                      crystallizable.




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