Page 133 - The Manga Guide to Biochemistry
P. 133
Now let’s talk about how fat is metabolized.
First, the fat in adipose tissue, triacylglycerol, is broken down into fatty acid
and glycerol by an enzyme called hydrolase. Hydrolase is a hormone-sensitive
lipase—note that this is different from a lipoprotein lipase, which we talked about
on page 112.
hydrolase fatty β-oxidation
Lipase acid
Fat Glycerol
triacylglycerol
Fatty acid is released into the blood and transported to the various organs and
muscles of the body, where it undergoes a chemical reaction called β-oxidation
(that’s beta oxidation).
Triacylglycerol hydrolase
adipose hormone-sensitive lipase
tissue
Fatty acid glycerol
Fatty acid glycerol endothelial
cell
blood
vessel
Fatty acid glycerol
Through blood vessels
to organs and muscles
β-0xidation
Biochemistry in Our Everyday Lives 119