Page 106 - Medicinal Chemistry Self Assessment
P. 106
Section 3 General Self Assessment Answers
2.1 Functional Group Characteristics
Structures for 1.1 and 2.1
and Roles
The bold has been removed. The exact same structures are in both of these chapters, but I have provided two
copies in the event you wanted that.
1. Shown below are the structures of warfarin, phenytoin, bromfenac, and salmeterol.
a. Identify each of the boxed functional groups.
A
F
C
E
D
Warfarin B Bromfenac G
Phenytoin
H
J K
I L
Salmeterol
Answer
Box Functional Group Name
A β-Dicarbonyl (enol form)
B Ketone B D
C A Phenyl ring; aromatic ring; aromatic hydrocarbon C O CH
O
D Imide H N S N 3
E Halogen (bromo) OH 2 H N O
F Primary aromatic amine; aniline O
G Carboxylic acid Sulfamethoxazole
Ibuprofen
H Primary hydroxyl group or primary alcohol
I Phenol or phenolic hydroxyl group
J Secondary amine
K Alkyl chain; aliphatic alkane
L Ether
95
Page 1 of 2