Page 293 - Pharmacognosy 2 PG303
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Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D

                                     Hypotensive ,                                     ■  Side effects :              widely used in
                                     Uterine stimulant).                               ✓  must not be taken for       bronchitis &  in
                                                                                                                                      .
                                  ▪  Berberine  and                                       a prolonged period ,        cough mixtures
                                     hydrastine produced                                  since this may disturb   ▪  In large doses ,it
                                     a hypotensive effect                                 the water  and              produces emesis.
                                     in laboratory                                        electrolyte balance .   ➢  Precautions
                                     animals ,but high                                 ✓  It should not be taken    ▪  Powdered squill is
                                     doses of hydrastine                                  during pregnancy and        white to white
                                     are documented to                                    lactation.                  yellowish brown ,
                                     produce an increase                                                              very hygroscopic
                                     in blood pressure .                                                              forming masses in
                                  ▪  Berberine                                                                        wet atmosphere
                                   ✓  exhibited                                                                       (must be kept on
                                       antipyretic                                                                    dehydrating agent
                                       activity three times                                                           like calcium oxide)
                                       as effective as                                                            ▪  It must be carefully
                                       aspirin.                                                                       handled as the
                                   ✓  Treat trachoma                                                                  calcium oxalate may
                                       (infectious ocular                                                             penetrate  the skin
                                       disease caused by                                                              and cause excessive
                                       Chlamydia                                                                      irritation.
                                       trachomatis)
                                   ✓  Anti-
                                       hyperglycemic
                                       activity
                                  ▪  A broad spectrum of
                                     antimicrobial
                                     activity
                                  ▪  Anticancer activity









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