Page 365 - Pharmacognosy 2 PG303 (1)
P. 365

Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D

 Shape and
 commercial product







 Constituents   Abietic acids (α,β,γ, 84%).   •  Resin (45-60%)   •  2.5-8% yellowish-green thick volatile
 They are formed, by the   •  Volatile oils (3-17%)   oils.
 effect of heat (Artifacts), from   •  Gum   •  25-40% resin.
 pimaric acid present                 •  60% gum of acacia type
 in natural turpentine
 Uses   •  Stimulant and diuretic.   •  Carminative    •  Antiseptic in mouthwash
 •  Ingredient of ointments and   •  expectorant    preparations.
 some varnishes.   •  antispasmodic    •  Uterine stimulant.
 •  Printing inks.   •   laxative     •  Recent studies revealed that
 •  Floor coverings.                      Myrrh is a new schistosomicidal
                                          drug
 Test for identity   Test for abietic acid    Freshly fractured surface of the tear:
 :
 0.5 g colophony + 5 mL   One drop ofH2SO4, a bright red or
 petroleum ether → shake →   reddish-brown color is produced
 filter →filtrate + equal volume   which
 of dil. Copper acetate T.S. →   changes to bluish violet color upon
 the pet.   washing with water.
 Ether layer assumes emerald    One drop of 50%
 green color    HNO3,
     a green color is produced
    Test for combined umbelliferone:
     1g Asafetida + 20mL (HCl + water)
    → Boil →filter into water made
    strongly alkaline with strong soln. of
 NH4OH → Blue fluorescence




     299
   360   361   362   363   364   365   366   367   368   369   370