Page 367 - Pharmacognosy 2 PG303 (1)
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Pharmacognosy-2 (PG303)                              Level 2                  Clinical Pharmacy-Pharm D


                                                 Animal - derived drugs

                                                        Cochineal

               Cochineal or coccus is the dried female insect Dactylopius coccus, family Coccidae
               containing eggs and larvae.

               Cochineal  insects  are  indigenous  to  Central  America  and  derived  from  Peru  and
               Canary Islands.










                Life History:   Both male and female insects emerge from eggs. The male is 1 mm.
                                long possessing wings, while female insect is 2 mm long and without
                                wings. After fecundation takes place, the female attaches itself to the
                                cacti by means of its proboscis and the male die. The female swell to
                                twice its size, owing to the presence of developing larvae, and develop
                                red colouring matter. In about fourteen days, the larvae matures and
                                escapes  from the  now  dead body  of the  parent. The  young  female
                                crawl about the plant and the males fly. This life cycle takes about six
                                weeks,  and  three  generations  of  insects  may  be  produced  in  one
                                season.
               Collection       The insects are brushed from the plants and most of them are killed.
               and              Killing  may  be  done  by  plunging  in  boiling  water  (black  grain,
                preparation:    purplish black) or by exposure to fumes of burning sulphur (Silver
                                grain, purplish grey).
                Characters:     Cochineal insects are 3.5 to 5.5 mm. long. They are oval in outline;
                                the convex dorsal surface shows 9-11 segments and no constriction
                                between head, thorax, and abdomen. The insects have a pair of seven-
                                jointed antennae and 3 pairs of minute legs. The surface bears tubular
                                glands which secrete wax.

                Constituents:








               Uses:              Natural colouring agent





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