Page 364 - Pharmacognosy 2 PG303 (1)
P. 364

Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D

                  Shape and
                  commercial product







                  Constituents              Abietic acids (α,β,γ, 84%).         •  Resin (45-60%)                          •  2.5-8% yellowish-green thick volatile
                                            They are formed, by the             •  Volatile oils (3-17%)                      oils.
                                            effect of heat (Artifacts), from    •  Gum                                     •  25-40% resin.
                                            pimaric acid present                                                           •  60% gum of acacia type
                                            in natural turpentine
                  Uses                      •  Stimulant and diuretic.          •  Carminative                             •  Antiseptic in mouthwash
                                            •  Ingredient of ointments and      •  expectorant                                preparations.
                                                some varnishes.                 •  antispasmodic                           •  Uterine stimulant.
                                            •  Printing inks.                   •   laxative                               •  Recent studies revealed that
                                            •  Floor coverings.                                                               Myrrh is a new schistosomicidal
                                                                                                                              drug
                  Test for identity         Test for abietic acid               Freshly fractured surface of the tear:
                                                                 :
                                            0.5 g colophony + 5 mL              One drop ofH2SO4, a bright red or
                                            petroleum ether → shake →           reddish-brown color is produced
                                            filter →filtrate + equal volume     which
                                            of dil. Copper acetate T.S. →       changes to bluish violet color upon
                                            the pet.                            washing with water.
                                            Ether layer assumes emerald          One drop of 50%
                                            green color                          HNO3,
                                                                                 a green color is produced
                                                                                Test for combined umbelliferone:
                                                                                 1g Asafetida + 20mL (HCl + water)
                                                                                → Boil →filter into water made
                                                                                strongly alkaline with strong soln. of
                                                                                NH4OH → Blue fluorescence




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