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Clinical Pharmacy-Pharm D Level Three 2 Semester 2024/2025 Pharmaceutical Technology (PT 607)
Lab (4): Determination of Tablet Diameter & Thickness
Types of tablets:
1- Immediate Release Uncoated Tablets:
– Release the drug immediately after oral administration.
– Usually no taste / stability issues.
2- Coated Tablets:
– For taste masking /stability issues /identification (coated with water soluble, dispersible
polymer-mixture of hydroxypropyl cellulose HPC / hydroxypropyl methyl cellulose
HPMC); coating readily ruptures in GI tract.
3- Enteric-Coated Tablets:
– For drugs inactivated or destroyed in the stomach or for those causing irritation to the
gastric mucosa; tablet passes through the stomach but disintegrates in the intestines where
absorption takes place.
– Excipients used for enteric coating include cellulose acetate phthalate, mixtures of fats
and fatty acids, etc.
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