Page 80 - Practical Technology 2025

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Clinical Pharmacy-Pharm D Level Three 2 Semester 2024/2025 Pharmaceutical Technology (PT 607)

5- Orange peel or film roughness:
It is surface defect resulting in the film being rough and nonglossy, appearance is
like that of an orange.

Causes remedies

Rapid drying Use mild drying conditions.

High solution viscosity and Use additional solvents to decrease

Inadequate spreading of the coating viscosity of solution.
solution before drying.

Revision

1. Which of the following tablet defects occurs as a result of spraying the
coating solution at very high temperature?
A: Orange peel

B: Blooming
C: Cratering
D: Blistering

2. How can you avoid the cratering of tablet coat?
A: Increase the rate of application of coating solution
B: Decreasing the viscosity of coating solution

C: Increase the viscosity of coating solution
D: Increasing the amount of lubricant

3. How can you avoid orange peel like tablet coat?

A: Decrease the viscosity of coating solution
B: Increase the viscosity of coating solution
C: Increase the drying temperature

D: Decrease the drying temperature

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