Page 88 - Practical Technology 2025

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Clinical Pharmacy-Pharm D Level Three 2 Semester 2024/2025 Pharmaceutical Technology (PT 607)

Problem 2

A Particle size analysis was carried out on a pharmaceutical powder using the

sieve method, the following data were obtained
• Calculate mean particle diameter
• Draw a cumulative % frequency under and over size

Sieve number Weight retained
Passed/retained
100/120 0.81
80/100 23.60
60/80 52.30
40/60 13.75
20/40 4.72
10/20 0.82

Solution

Mid-point of Weight
size range retained
Frequency
(n)

110 0.81
90 23.60
70 52.30
50 13.75
30 4.72
15 0.82

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