Page 89 - Practical Technology 2025
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               Clinical Pharmacy-Pharm D        Level Three        2  Semester       2024/2025      Pharmaceutical Technology (PT 607)


               Problem 3

               A granule size analysis was carried out on calcium carbonate granules using the

               sieve method, the following data were obtained
                   •  Calculate the mean granule diameter

                   •  Draw a cumulative % frequency under and over size
                                      Mean diameter                 Weight retained

                                            1800                            12
                                            1400                            14
                                            1100                            30
                                             900                            15
                                             700                            10
                                             450                             9

                                             150                             8

               Solution
                 Mid-point of         Weight
                  size range         retained
                                    Frequency
                                        (n)

                     1800                12
                     1400                14
                     1100                30

                      900                15
                      700                10
                      450                9
                      150                8


















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