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AROUND THE REGION
TM
Back Cover Story: Prescription for Exercise
Continued from page 56 endothelial cells, and lung, a possible cannabinoid levels and changes in mood could be involved in both the psycholog-
moderate intensity dramatically in - role for the endocannabinoid system in before and after sessions with varying ical and biological response to exercise.”
creased concentrations of anandamide in mediating certain physiological respons- levels of intensity. The study found that Through discovering the links between
blood plasma. es to exercise may exist. subjects experienced a significant boost exercise and the endocannabinoid sys-
The runner’s high has been described Gregory Gerdeman and other col- in endocannabinoids and improvements tem, one goal is to develop new treat-
subjectively as happiness, elation, a feel- leagues investigated how exercise influ- in mood following prescribed moderate- ments for mental health conditions that
ing of unity with one’s self and/or nature, ences the endocannabinoid levels of two intensity exercise. include exercise. Exercise is an easily
peacefulness, inner harmony, boundless mammalian natural athletes - humans Data from 17 women who suffer with accessible, free option to feel well, stay
energy, and a reduction in pain sensation. and dogs - and a low activity species - fer- depression was analyzed during the healthy, improve brain health, strengthen
An exercise induced altered state of con- rets. The team published their discovery study, where each woman completed bones and muscles, and help optimize
sciousness has long been appreciated by that animals that evolved for endurance two, thirty-minute exercises on station- one’s endocannabinoid system. It is a
endurance athletes. This sounds similar exercise benefit from endocannabinoids ary bikes at both moderate and preferred time you can connect with yourself or
to the way we discuss how one feels while animals that did not don't experi- intensity. The data showed that both ses- others, feel powerful, free, and be out in
while on psychedelic medicine. There is ence the pleasures, leading them to pro- sions on the bike improved mood, but nature. Perhaps if I prescribed exercise
actually cross talk that exists between pose that natural selection used the only showed an increase in endocannabi- more to my patients on my prescription
our Cannabinoid receptor in the brain endocannabinoid system to motivate noid levels for moderate intensity exer- pad, they might be more likely to respect
(CB1) and our classic serotonin psyche- endurance exercise in humans. The team cise. There was no difference for pre- the treatment plan or perhaps we should
delic receptor 5HT2A. Therefore, using publishes their discovery in The Journal ferred intensity. get our patients familiar with therapies
cannabis can actually cause a similar of Experimental Biology. The study also shows there is some that do not need to be picked up at a
altered level of consciousness or psyche- 'Inactive people may not be fit enough correlation between prescribed exercise pharmacy…
delic feeling because of the dimerization to hit the exercise intensity that leads to and increase in mood, as opposed to pre-
between receptors. this sort of rewarding sensation.' ferred exercise. The same team complet- Dr. Michelle Weiner, Spine and Wellness
Because activation of the endocannabi- However, inactive individuals can be ed a similar study in 2016 that looked at Centers of America, can be reached at
noid system reduces pain sensations, and helped to build up their exercise toler- the effect of exercise on brain-derived (305) 974-5533 or
alters emotional and cognitive processes, ance until they cross the threshold where neurotrophic factor or BDNF, a protein mweiner@spinewellnessamerica.com.
this finding has implication for some of they become motivated to exercise by that regulates neuron growth and sur-
the psychological effects that accompany endocannabinoids. vival. People with depression typically
Raichlen, D. A., Foster, A. D., Gerdeman, G. L.,
exercise. As a result of the presence of Another study performed by re - have lower levels of BDNF. The 2016 Seillier, A. and Giuffrida, A. (2012). Wired to run:
cannabinoid receptors in muscle, skin, searchers in Wisconsin measured endo- study found that when women with exercise-induced endocannabinoid signaling in
depression were prescribed an exercise humans and cursorial mammals with implications
session similar in intensity to exercise for the 'runner's high'. J. Exp. Biol. 215, 1331-1336.
jeb.biologists.org/content/215/8/1331.abstrac
they selected, their BDNF levels were sig-
nificantly higher following the pre- Serum Endocannabinoid and Mood Changes
after Exercise in Maj... : Medicine & Science in
scribed session. Therefore, “Having
Sports & Exercise (lww.com)
someone else prescribe the exercise
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54 May 2021 cannabisnewsflorida.com Cannabis News Florida