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UNIT 1
               MODULE 2: GENETICS, VARIATION AND NATURAL SELECTION (cont’d)


                SPECIFIC OBJECTIVES                 EXPLANATORY NOTES            SUGGESTED PRACTICAL
                                                                                 ACTIVITIES

                Aspects of Genetic Engineering (cont’d)

                Students should be able to:

                4.2.     explain  the  basic  steps   An overview of the process
                         involved  in  Recombinant   including  the  isolation  of
                         DNA (rDNA) technology;      genes;  cloning  of  genes;
                                                     vectors.  Use  examples
                                                     including         insulin
                                                     production.

                4.3.     discuss  the  successes  and   Concept of gene therapy.
                         challenges of gene therapy   Use  case  study  examples
                         in modern medicine; and,    including cystic fibrosis.

                4.4.     discuss the implications of   Medical,   agricultural,
                         the  use  of  genetically   ethical    and     social
                         modified  organisms  on     implications.
                         humans       and      the
                         environment.


                5.       Natural Selection

                Students should be able to:

                5.1.     explain              how    Examples     such     as
                         environmental  factors  act    resistance  to  antibiotics,
                         as   forces   of   natural   Biston         betularia
                         selection;                  (peppered  moth),  the
                                                     Trinidadian  guppies  and
                                                     the Dominican anole.

                5.2.     explain    how    natural   Directional, disruptive and
                         selection may be an agent   stabilising    selection;
                         of constancy or an agent of   knowledge of appropriate
                         change;                     graphs is required.

                5.3.     discuss  natural   selection   Darwin’s   theory,   its
                         as   a    mechanism    of   observations        and
                         evolution;                  conclusions.




                            CXC A10/U2/17
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