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UNIT 2
               MODULE 3: APPLICATIONS OF BIOLOGY (cont’d)


                SPECIFIC OBJECTIVES                  EXPLANATORY NOTES           SUGGESTED PRACTICAL
                                                                                 ACTIVITIES

                2.       Immunology

                Students should be able to:

                2.1.     define  the  term,  “immune
                         response”;

                2.2.     distinguish  between  the   Include  the  sequence  of
                         humoral  and  the  cell-    events  involved  in  each
                         mediated         immune     response.
                         responses;

                2.3.     explain the role of memory   T- and B- memory cells.
                         cells   in   long-   term
                         immunity;

                2.4.     compare  the  origin  and   Include the types of T-cells
                         maturation  of  B-  and  T-   and  their  function  (refer
                         lymphocytes;                to  HIV);  B-cells  and  their
                                                     function.

                2.5.     describe the mode of action   Revision  of  phagocytosis;
                         of phagocytes;              include role of mast cells
                                                     and            histamine
                                                     production;  complement;
                                                     phagocytes  as  antigen-
                                                     presenting cells.

                2.6.     relate   the    molecular   Use of labelled diagram  of
                         structure   of  a   typical   typical  antibody showing
                         antibody  molecule  to  its   its  ‘Y- shaped’  structure;
                         function;                   include  the  function  of
                                                     the     various   parts;
                                                     specificity  of  antibody  to
                                                     antigen.

                2.7.     state  what  is  meant  by  a
                         monoclonal antibody;

                2.8.     describe   the   use   of   The    anticancer   drug,
                         monoclonal  antibodies  in   MabThera;        details
                         diagnosis and treatment;    required  of  the  use  of
                                                     monoclonal  antibodies  in
                                                     pregnancy testing.

                            CXC A10/U2/17
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