Page 162 - Pharmacology Mnemonics and Short Notes

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o Protective layer is form to prevent loss by widespread
production of plasmin

Alteplase

 Normal human plasminogen activator

Reteplase

 Mutated form of human tPA (fast + longer duration of action)

Tenectiplase

 Human mutated form with longer half life

Streptokinase

 Obtained from bacteria

 Non selective to fibrin bound to plasmin

Uses

PCR

P  pulmonary embolism

C coronary artery angiography in coronary artery thrombosis

R  recanalize coronary artery

Adverse effects

ABC

A  antibody formation against streptokinase

B  increased bleeding

C  cerebral haemorrhage

Antiplatelet drugs

Contents

Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman