Page 163 - Pharmacology Mnemonics and Short Notes
P. 163
155
1) ADP receptor inhibitors
Ticlo (Ticlopindine and clopidogrel)
Irreversibly inhibit platelet ADP receptor
Uses
Ticlo Cap
C acute coronary syndrome
A prevent and treat arterial thrombosis
P after PCI (percutaneous coronary intervention) to
prevent restenosis
2) Phosphodiesterase inhibitors
Dieaseterase Dipyridamole
o Inhibit adenosine uptake
o Inhibit phosphodiesterase that degrade cAMP.
Uses
o Prevention of thromboembolic complications of cardiac valve
replacement
o With Aspirin to prevent secondary ischemic stroke
3) Aspirin
Mechanism
Non-selective irreversible inhibitor of COX enzyme
Result reduced production of thromboxane A 2 by platelets ( TxA 2 is
potent stimulator of platelets)
Uses as anticoagulant
o
o P myocardial infarction
Contents
Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman
