Page 242 - Pharmacology Mnemonics and Short Notes
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234


             Last line of treatment  due to lethal drug dietary interactions

        Mao in ISP (international school of Pakistan)

               I  isocarboxazid


               S  selegeline

               P  phenlezine

        Mechanism






































        Inhibit MAO enzyme (two isoforms A & B)  prevent breakdown of
        monoamine neurotransmitters (example serotonin, dopamine and
        melatonin)  increase their availability


        Uses

        In atypical depression.

        Interactions


              Catabolism of dietary amines is inhibited
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   Pharmacology Mnemonics and Short Notes                                              By Muhammad Ramzan Ul Rehman
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