Page 278 - Pharmacology Mnemonics and Short Notes
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270




             Non insulin anti diabetic




                                           drugs












                Insulin                                alpha glucosidase
            secretagogues           Biguinides             inhibitors        Thiazolidinediones






        Insulin secretagogues

                                                                                                 +
             Stimulate endogenous insulin release  by premature closure of K
               channels in the pancreatic beta cell membrane




                  Insulin             closes K +         depolarized           release of
              secretogogues          channels              the cell              insulin





        Most of them belong to Sulfonylureas
        Second generation sulphonylureas

               Gly (My pride – my bride)


               Gly + My Pride  Glimepiride

               Gly + Pride (Pizide)  Glipizide

               Gly + Bride  Glyburide

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   Pharmacology Mnemonics and Short Notes                                              By Muhammad Ramzan Ul Rehman
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