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 Fluid flows in CNS  so used in meningitides  Cryptococcal
meningitides

 If someone engulf his flu secretion it will first go to his oropharynx
then into oesophagus

o Oropharynx  Oropharyngeal Candidiasis

o Oesophageal  Oesophageal candidiasis

Itraconazole

It is used in ABC

A  Aspergillus infection

B  Blastomycosis infection

C  Chromoblastomycosis & Candidiasis

Voriconazole

Vori  invasive aspergilosis resistant to other drugs

Posaconazole

P  used in prophylaxis of fungal infections

Toxicity

Voriconazole  Visual disturbances

Ketoconazole  munday ko kuri bna deti hay

 Interfere synthesis of adrenal and gonadal hormones

o Gynecomastia (enlarged breast in male)

 In females  menstrual disturbances

For all  Diarrhoea, vomit, Rash and hepatotoxic

 They all inhibit Cyt p450

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Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman