Page 323 - Pharmacology Mnemonics and Short Notes

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 Prophylaxis tuberculosis

 Persons in close contact with Tuberculosis person

 Leprosy  delay emergence of resistance

 With Vancomycin  Methicillin resistant staph aureus

Toxicity

Rifampicin in NEPAL

N  Nephritis
E  Excite P450 metabolizing enzyme

P  Proteinuria
A  Anemia
L  Liver dysfunction

Ethambutol

Mechanism

Inhibit arabionosyl transferase (encoded by emb [ab] gene)

Resistance

Emb gene mutation

Uses

 Tuberculosis in combination with others

Toxicity

 Ethambutol  E  Eye

o Visual disturbances

o Optic neuritis

o Red green colour blindness

Pyrazinamide
Contents Require bioactivation

Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman