Page 11 - Extemp Marking Scheme

FAR 222/3 Dosage Form II Extemporaneous Exercise – Marking Scheme 2019 – 2020

Exercise 2.5 C

SCHOOL OF PHARMACEUTICAL SCIENCES
UNIVERSITI SAINS MALAYSIA
11800 USM, PENANG, MALAYSIA
Tel: 04-6532211 Fax: 04-6570017

NAME: DATE:
ADDRESS: AGE: SEX:

Metaraminol IV 50 mg b.d. × 4/7 – Dose change to 5 mg – 1M
G.Eiffel
G. Eiffel MD

Question:
1. Complete a pharmaceutical production document for this formulation as a multidose injection
and prepare the formulation accordingly. (30 marks)

NAME OF BATCH
PRODUCT NO. DATE
TARE MEASURED CHECKED
QUANTITY
FORMULA – 3M USED CHECKED BY BY
BY
Metaraminol tartrate 0.76 g 1M
20 mL
(Stock
Chlorocresol 1M
0.2
%w/v)
Sodium metabisulphite (0.1%) 0.03 g* 1M
qs ad
Water for injection 1M
40 mL

Size 20 mL
CONTAINER -3M Type Multidose glass vial FILTRATION Sintered glass filter Grade
(1M ea) Rubber closure and metal -1M 3 (15 – 40 µm)
Closure type cap
Equipment used Aseptic filtration
STERILISATION Duration -
-3M (1M ea) Condition
(temperature, Laminar flow hood -1M
pressure etc) Swinnex filter holder with a 0.22 µm membrane filter -1M

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