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SCIENCETuesday 26 January 2016

Implanted coils help some lung disease patients, study says 

LINDSEY TANNER               This photo depicts an X-ray of lungs following the PneumRx En-                        a Northwestern University      Implanted coils and valves,
AP Medical Writer            dobronchial Coil treatment procedure. A novel, minimally in-                          lung specialist who was in-    another minimally inva-
CHICAGO (AP) — A nov-        vasive way to treat severe breathing problems caused by lung                          volved in the U.S. study.      sive treatment, are used
el, minimally invasive way   disease showed modest but promising benefits in a small French                        “Every little increment of     abroad but are consid-
to treat severe breathing    study.                                                                                something that could work      ered experimental in the
problems caused by lung                                                                                            in COPD is significant. There  United States.
disease showed modest                                                                            (BTG PLC via AP)  are a lot of people with this  Results from the study were
but promising benefits in a                                                                                        disease,” Kalhan said.         published recently in the
small French study.          last month in preliminary re-   provide real benefits for                             COPD, which includes           Journal of the American
The technique involves in-   sults from a U.S. study.        a select group but won’t                              emphysema and chronic          Medical Association.
serting several small metal  The French results suggest      work for many COPD pa-                                bronchitis, causes normally    The French health ministry
alloy coils through a scope  that coil treatment may         tients, said Dr. Ravi Kalhan,                         elastic airways to stiffen     paid for the study. Two of
into the lungs, aiming to                                                                                          and sometimes swell. It        the researchers reported
tighten diseased tissue and                                                                                        affects 65 million people      involvement in previous re-
open up healthy airways.                                                                                           worldwide, including at        search funded by the coil
It’s among experimental                                                                                            least 15 million mostly older  maker, along with travel
alternatives to major lung-                                                                                        Americans, and is a lead-      and speaker fees.
reduction surgery for pa-                                                                                          ing cause of death and         The study involved 100 pa-
tients with emphysema, a                                                                                           disability.                    tients randomly assigned
common feature of chron-                                                                                           Patients often have diffi-     to receive usual care or
ic obstructive pulmonary                                                                                           culty climbing stairs, show-   coil treatment at 10 hospi-
disease, or COPD.                                                                                                  ering or even dressing with-   tals in France.
The treatment helped                                                                                               out feeling out of breath.     Coil patients each got
patients to walk further                                                                                           Usual treatment may in-        about 20 of the devices.
and reduced symptoms                                                                                               clude inhaled medicine,        The coils are a few inch-
including coughing and                                                                                             often steroids, exercise,      es long outstretched but
breathlessness, the French                                                                                         breathing assistance with      spring into a circular shape
researchers reported. The                                                                                          portable oxygen tanks, or      in the lungs.
coil manufacturer, Lon-                                                                                            sometimes major surgery        After six months, patients
don-based BTG PLC, an-                                                                                             to removed diseased lung       were given a six-minute
nounced similar benefits                                                                                           tissue.                        walking test to see they
                                                                                                                                                  could walk at least 59
Drug industry, governments to combat superbugs                                                                                                    yards (54 meters) farther
                                                                                                                                                  than they did at the start.
LINDA A. JOHNSON             tic tests and nine indus-       parasites and fungi, and                              scriptions and the stronger    Only 18 coil patients
Associated Press             try groups have signed a        declining industry research                           microbes survive and mul-      achieved the goal, but
TRENTON, N.J. (AP) — Doz-    groundbreaking agree-           in the field. A key factor                            tiply. Taking antibiotics for  that was twice as many
ens of makers of medi-       ment to work with govern-       driving those problems is                             viruses and other nonbac-      as in the usual treatment
cines and diagnostic tests   ments and each other to         the relatively low prices                             terial infections also con-    group.
have joined together in an   prevent and improve treat-      infection-fighting medi-                              tributes to resistance. And    At six months, coil patients
unprecedented effort to      ment of drug-resistant in-      cines bring, compared to                              widespread use of antibi-      could walk on average 23
tackle “superbugs” — in-     fections. The effort is sorely  many drugs patients take                              otics to spur faster growth    yards (21 meters) farther
fections that increasingly   needed. Many common in-         for years for chronic con-                            of livestock raised for food   than the other group.
don’t respond to drugs and   fections no longer respond      ditions. Bacteria and other                           exacerbates the problem.       Their scores on a question-
threaten millions of people  to conventional drugs,          microbes can naturally de-                            Meanwhile, in poor coun-       naire about symptoms and
in countries rich and poor.  mainly due to overuse of        velop resistance to drugs,                            tries, many people can’t       quality of life were also bet-
Altogether, 74 drugmak-      antibiotics, few new drugs      particularly when patients                            afford these medications       ter than the other group,
ers, 11 makers of diagnos-   to fight bacteria, viruses,     don’t take all of their pre-                          and die unnecessarily.q        although that wasn’t the
                                                                                                                                                  study’s main measure.q
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