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Cytoplasmic fine speckled

pattern (AC-20)

HEp-2 cells. The cell nuclei also show distinct sharp dots in

many cases. According to recent findings, Jo-1 target

antigens are not solely localised in the cytoplasm, but are

also found in the cell nucleus in some species

Primate liver,the cytoplasm is only slightly stained.

The fluorescence cannot be used for diagnostics.