Page 1232 - Equine Clinical Medicine, Surgery and Reproduction, 2nd Edition
P. 1232

CHAPTER 12

                                                 SKIN
  VetBooks.ir                                   Tony Yu                                         1207













          The skin is recognised as the body’s largest   to eliminate these early in the course of the investi-
          organ, and among its more important tasks are   gation. The use of a formulated examination sheet
          protection of the horse against the environ-   allows a structured and thorough approach. With
          ment, thermoregulation (sweating and heat      long-standing cases it is helpful to list the follow-
          conservation), sensory perception, secretory   ing in chronological order: (1) notes of disease prog-
          function, pigmentation and acting as an indica-  ress; (2) changes in feed; (3) location; (4) events; and
          tor of the horse’s general health. The careful   (5) other riders or tack that have been used. A list
          assessment of clinical signs, understanding their   should also be made of all or any previous medica-
          significance in relation to a disease process, and   tions, not only for the skin condition itself, but also
          a basic understanding of skin morphology and   for any other medical or surgical condition that the
          function allow the accumulation of sets of indi-  horse has had in the past. The results of any tests and
          cators of disease that help the clinician to reach   follow-up treatments should also be included.
          an accurate diagnosis.
            The initial approach is to determine the     Clinical examination
          predominant clinical signs. The three most     The clinical appraisal of the horse involves looking
          common components of skin disease are pru-     at the general health and body condition and visu-
          ritus, hair loss and nodular lesions. Secondary   ally assessing the obvious sites of the skin problem,
          changes include dry dermatosis (scaling and    which may be localised or generalised. A complete
          crusting), moist dermatosis (weeping and       clinical examination should be performed, as there
          seeping) and pigmentary changes. The history   may be indicators suggesting that organ function
          of the disease, any treatment already given,   tests should be carried out. Some examples are endo-
          the owner’s views, and then the appearance     crine diseases such as equine Cushing’s disease and
          of the horse should be examined to see if these   anhidrosis, both of which have marked effects on the
          three important signs, plus any or all of the   hair coat. Immune-mediated diseases are rare, but
          three secondary conditions, are part of the    diseases such as systemic lupus erythematosus (SLE)
          disease pattern. While it may be more scientifi-  also have multisystemic effects and their diagnosis
          cally ‘correct’ to make an approach based on   requires the combination of skin biopsy, clinical
          the causal agent or agents, these may not be   signs and positive antinuclear antibody (ANA) and
          clear until tests are taken and the diagnostic   lupus erythematosus (LE) cell tests. Fungal organ-
          process begun.                                 isms, such as Phycomycetes, can show both generalised
                                                         and cutaneous forms. Liver toxicosis due to feed tox-
          EXAMINATION                                    ins or poisonous plants may show skin changes.
                                                           The skin lesions should be carefully evaluated.
          History                                        Various diagnostic skin tests are available for use
          The historical record should cover the clinical his-  and contact should be made with a pathology labora-
          tory  of  the  disease  process,  an  extensive  review  of   tory to enable discussion of the clinical features of a
          the horse’s environment and feeding regimes, and   case and to receive advice on the most appropriate
          should identify any outside source(s) of causal agents   samples to collect.
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