Page 1272 - Equine Clinical Medicine, Surgery and Reproduction, 2nd Edition
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Skin                                          1247



  VetBooks.ir  cell  division. As secondary inflammatory changes   12.40
          occur around them, they develop into typical
          tumours of the skin, which may present as enlarged
          nodules  or  verrucous  forms,  or  develop  ulcerative
          changes and necrosis.
            Swellings also include urticarial swellings,
          abscesses and body swellings such as hernias and
          cysts. Urticaria is covered later in this chapter (see
          p. 1281). Abscesses are localised fluid- to solid-filled
          lesions. They are the result of inflammatory changes,
          usually related to trauma and/or infection, and con-
          sist of dead cells, debris and local tissue components   Fig. 12.40  Equine molluscum contagiosum is due to
          that have liquefied through proteolytic and histo-  a poxvirus occurring around genital organs of mares
          lytic enzymes. Although usually related to infection,   and stallions and presents with small papules and a
          abscesses can be sterile.                      waxy skin surface. (Photo courtesy DW Scott; reprinted
            Tumours, nodules and swellings tend to be pri-  from Pascoe RR and Knottenbelt DC (1999) Manual
          mary disease sites and in horses are infrequent mani-  of Equine Dermatology, WB Saunders, with permission)
          festations of systemic disorders. The major disease
          considerations in establishing a differential diagno-
          sis are physical causes, infectious diseases, hypersen-  EQUINE VIRAL ARTERITIS (EVA)
          sitivity reactions, sterile inflammatory diseases and
          neoplasia.                                     Definition/overview
            Injuries to the skin and underlying tissues may   EVA  is  a  viral  disease  associated  with  abortion,
          result in superficial trauma to the epidermis right   infertility  and  skin  disease.  Some  strains  are  rela-
          through to joint, bone and muscle injury. This is   tively avirulent and infection may go unnoticed and
          manifested by an alteration in the normal contour of   undiagnosed (see Chapter 2.1, p. 454).
          the skin and may lead to diagnostic confusion among
          cellulitis, haematoma, bursitis and hernias.   PAPILLOMATOSIS
            Bruising is extravasation of blood into the der-
          mis and epidermis without severe dislocation of  Definition/overview
          the external epidermal layer. Haematoma involves   Papillomatosis is a viral skin disease characterised by
          the rupture of blood vessels in subcutaneous tis-  small warts on the nose, lips, around the eyes, inside
          sues leading to extravasation of blood into the   the ear and very occasionally on the neck and limbs.
          interstitial tissue. Cellulitis is extravasation of cel-
          lular fluid into tissue spaces, which may or may not  Aetiology/pathophysiology
          be infected.                                   Seven Equus caballus papillomaviruses (EcPV) have
                                                         been described in horses and each has been associated
          INFECTIOUS CAUSES – VIRAL                      with one of three different conditions: (1)  EcPV1
                                                         with classical warts; (2) EcPV2 and EcPV7 with
          EQUINE MOLLUSCUM CONTAGIOSUM                   genital plaques, carcinoma in situ and SCCs; and
          (UASIN GISHU DISEASE)                          (3) EcPV3–6 with aural plaques. Additionally, aber-
                                                         rant  species  infestation with  bovine  papillomavi-
          Definition/overview                            ruses (BPV1 and BPV2) induces equine sarcoids.
          This is a mild contagious cutaneous infection caused   Transmission can occur via direct contact with an
          by unclassified poxviruses. Lesions may occur on the   infected  horse,  indirectly  through  contaminated
          penis, prepuce, scrotum, mammary glands, thighs,   fomites, sexual transmission or trauma including
          axillae and muzzle (Fig. 12.40).               insect bites.
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