Page 1276 - Equine Clinical Medicine, Surgery and Reproduction, 2nd Edition
P. 1276

Skin                                          1251



  VetBooks.ir  Differential diagnosis                    results in discharge of pus, which is mucoid, with the
                                                         presence  of  whitish  yellow  granules.  These  gran-
          Fungal  folliculitis;  dermatophytosis;  dermatophi-
          losis;  onchocerciasis;  other  bacterial  pyodermas;
                                                         therefore an important diagnostic specimen. The
          equine demodicosis.                            ules typically contain the infective organism and are
                                                         lesion may present on the shoulder, neck, withers,
          Diagnosis                                      ventral abdomen, udder or limbs. Chronically dis-
          Deep biopsy for culture and susceptibility testing is   charging sinuses at the scrotum may progress to fibro-
          carried out.                                   sis and abscessation of the spermatic cord and testes.
                                                         Metastasis of purulent lesions to internal organs such
          Management                                     as lung, liver, spleen and kidney may occur.
          Surgical drainage of larger lesions may be necessary.
          This should be followed by skin washes with acceler-  Differential diagnosis
          ated hydrogen peroxide or chlorhexidine solution. If   Habronema infestation; pythiosis; foreign body sinus
          surgical drainage has been required, treatment with   drainage.
          parenteral antibiotics such as penicillin (24,000 IU/
          kg i/m q24 h for 3–7 days) or oral antibiotics such  Diagnosis
          as trimethoprim/sulphadiazine (30 mg/kg p/o q24 h   Diagnosis is based on the history of the type of
          until 7 days past clinical resolution) may be required.   injury and biopsy for histopathology.
          All  in-contact  equipment  must  be  fumigated  and
          hygiene improved.                              Management
                                                         Surgical excision should be performed, with subse-
          Prognosis                                      quent administration of antibiotics such as penicillin
          The prognosis is guarded and this condition can be   (24,000 IU/kg i/m q24 h for 3–7 days) or oral antibi-
          very slow to resolve.                          otics such as trimethoprim/sulphadiazine (30 mg/kg
                                                         p/o q24 h until 7 days past clinical resolution).
          BACTERIAL GRANULOMA
          (BOTRYOMYCOSIS)                                Prognosis
                                                         The prognosis is guarded, because reinfection can
          Definition/overview                            occur following surgery, with a return of a similar
          Botryomycosis is a pyogranulomatous lesion associ-  clinical entity.
          ated with skin injury.

          Aetiology/pathophysiology                      12.46
          It is caused by lacerations, puncture or a post-
          surgical complication of the skin followed by infec-
          tion, typically by Staphylococcus spp. and occasionally
          Actinomyces spp., which slowly progresses to multiple
          miliary interlinking abscesses discharging through
          multiple sinuses.

          Clinical presentation
          Alopecia, a slowly healing wound, induration of the
          edges and chronic purulent discharge from one or
          more sinuses, with rosette formation of granulation
          tissue around sinuses, may be observed (Fig. 12.46).   Fig. 12.46  Bacterial granuloma (botryomycosis
          The lesion may be large (10–20 cm in diameter), soli-  lesion) showing many discharging sinuses in the
          tary and resemble a tumour. Rupture of the nodules   granulation tissue.
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