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Intussusception   561


           •  Granulomatous uveitis with accumulation   Acute General Treatment   •  Iris melanomas in cats are malignant tumors,
                                                                                    and metastasis is possible.
             of inflammatory nodules within iris stroma  Primary intraocular tumors:  •  Primary  intraocular  sarcomas  in  cats  are
  VetBooks.ir  Initial Database                •  Due to the metastatic potential, enucleation   locally aggressive and often metastasize.  Diseases and   Disorders
                                               •  Enucleation is indicated for irreversible blind-
           •  Other causes of uveitis, glaucoma, intraocular
             hemorrhage
                                                ness and pain due to secondary glaucoma
                                                intraocular sarcoma in cats.
           •  Ophthalmic exam (p. 1137), including evalu-  is indicated for iris melanoma and primary    PEARLS & CONSIDERATIONS
             ation of vision and pupillary light reflexes,   •  Conservative  monitoring  alone  may  be   Comments
             measurement of intraocular pressure; direct   justified in older dogs based on likely slow   •  Assessment of vision is the primary factor
             visualization of mass may allow conclusive   growth of primary tumor.  in determining treatment recommendation.
             diagnosis.                        •  Sector iridectomy may provide incomplete   If eye has functional vision, laser treatment
           •  Ocular ultrasonography may confirm and   excision and is often accompanied by hemor-  should be considered for localized pigmented
             delineate mass that cannot be directly   rhage and secondary glaucoma; may be only   lesions; if eye is blind, enucleation is
             visualized because of location or lack of   surgical option other than enucleation for   recommended.
             clarity of ocular media. Tumor appears as a   nonpigmented tumors    •  For  malignant  melanoma  and  sarcoma  in
             hyperechoic mass within iris or ciliary body   •  Diode  laser  treatment,  transcorneally  or   cats, enucleation is advisable. Areas of pro-
             and may be difficult to differentiate from   through a limbal incision, is often effective   gressive but localized iris hyperpigmentation,
             organized hemorrhage.              for pigmented uveal tumors.         unconfirmed as neoplastic, can be treated by
           •  Systemic evaluation to rule out metastatic   •  Diode laser treatment, possibly in combina-  diode laser and monitored carefully.
             disease (CBC, serum biochemistry panel,   tion with surgical debulking, is very effective
             urinalysis, thoracic and abdominal radio-  for treatment of limbal melanomas.  Prevention
             graphs and ultrasonography)       Secondary  intraocular  tumors:  treatment  is   Iris melanoma in dogs: avoid breeding affected
                                               directed at primary neoplasm if possible. If   individuals or their close relatives.
           Advanced or Confirmatory Testing    systemic prognosis warrants, enucleation may
           •  Aqueocentesis may not be diagnostic because   be indicated for comfort.  Technician Tips
             tumors often do not exfoliate cells into the                         The appearance of intraocular neoplasia is
             aqueous; most valuable for lymphoma  Possible Complications          extremely variable. It is important to monitor
           •  Fine-needle  aspiration  of  mass  is  often   •  Laser  treatment  of  large  lesions  may  be   the intraocular pressure of these patients to
             nondiagnostic due to inadequate size of   accompanied by significant inflammation   check for secondary glaucoma.
             sample.                            and may precipitate secondary glaucoma.
           •  Biopsy  of  mass  may  be  accompanied  by   •  Regrowth  of  tumor  is  possible  after  laser   SUGGESTED READING
             hemorrhage.                        treatment.                        Labelle AL, et al: Canine ocular neoplasia: a review.
                                                                                   Vet Ophthalmol 16:3-14, 2013.
            TREATMENT                          Recommended Monitoring             AUTHOR: Cynthia S. Cook, DVM, PhD, DACVO
                                               Long-term monitoring to detect recurrent
           Treatment Overview                  growth is indicated after laser treatment.  EDITOR: Diane V. H. Hendrix, DVM, DACVO
           Treatment is based on assessment of presence
           of vision and potential to preserve comfortable    PROGNOSIS & OUTCOME
           globe. Goals are to prevent progressive growth
           of tumor (preserving vision and comfort) and   •  Primary neoplasms of the iris, ciliary body,
           alleviate discomfort caused by secondary   and limbus in dogs are almost always benign
           glaucoma in blind eye.               and rarely metastasize.





            Intussusception                                                                        Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  GENETICS, BREED PREDISPOSITION       duodenogastric, enteroenteric, enterocolic,
                                               Siamese and Burmese cats, German shepherds,   cecocolic.
           Definition                          and Shar-peis may be predisposed.  •  Intussusception most commonly occurs in
           •  Invagination  of  one  segment  of  the                               direction of normal peristalsis, with intus-
             gastrointestinal (GI) tract into the lumen   RISK FACTORS              susceptum as proximal segment, but reverse
             of an adjacent segment            •  Infectious gastroenteritis (parasitic, bacterial,   can also occur (e.g., GEI).
           •  Intussusceptum is the invaginated segment,   or viral), foreign body ingestion, intestinal   •  More  than  one  site  can  be  involved,  or
             and the intussuscipiens is the outer or envelop-  mass/neoplasia, previous surgery peritonitis,   two invaginations may occur at the same
             ing segment.                       organophosphate intoxication, parturition in   site.
                                                queens
           Epidemiology                        •  Megaesophagus/abnormal esophageal motility   HISTORY, CHIEF COMPLAINT
           SPECIES, AGE, SEX                    for GEI.                          •  Diarrhea, hematochezia, vomiting, anorexia,
           •  Intestinal intussusception usually occurs in   Clinical Presentation  lethargy, and weight loss
             animals < 1 year old unless associated with                          •  Respiratory distress if GEI
             neoplasia.                        DISEASE FORMS/SUBTYPES             •  Signs can be acute or chronic.
           •  Gastroesophageal intussusception (GEI) is   •  Any of the following sites can be involved:
             most common in dogs < 3 months old.  gastroesophageal (p. 468), pylorogastric,

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