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1151.e2  Peritoneal Dialysis




            Peritoneal Dialysis
  VetBooks.ir


                                              •  Peritoneal dialysis catheters
           Difficulty level: ♦♦♦
                                                ○   Dogs: tunnel all catheter types subcutane-  •  Electrolyte imbalances (hypochloremia, hypo-
                                                                                   kalemia,  hyponatremia,  hypomagnesemia,
           Overview and Goal                      ously to decrease the risk of dialysate leak   hypocalcemia, hyperkalemia, hyperglycemia)
           Exchange of dialyzable solutes and fluid between   and the incidence of peritonitis. Cats:   Uncommon:
           the peritoneal vessels and the dialysate solution.   secure with purse-string suture to linea   •  Overhydration and pleural effusion
           Exchange  occurs  across  the  semipermeable   alba                   •  Hemorrhage
           peritoneal membrane due to diffusion, ultra-  ○   Percutaneous placement with trocar or   •  Dialysis dysequilibrium
           filtration, and convection.            guide wire–inserted silicon tube (e.g.,   •  Hypoalbuminemia
                                                  Mila chest tube) restricted to emergency   •  Septic peritonitis
           Indications                            situations or for short-term use because
           •  Acute kidney injury unresponsive to con-  omental obstruction is a common   Procedure
            ventional medical management          occurrence.                    •  General  anesthesia  for  mini-laparotomy
           •  Hyperkalemia  (p.  495)  or  hypercalcemia   ○   Mini-surgical approach options include   approach in stable patients or sedation and
            (severe) (p. 491)                     fenestrated, modified silicone catheters   regional anesthesia in critical patients or
           •  Intoxication from ethylene glycol (<24 hours   with or without Dacron cuffs such as   percutaneous technique
            after ingestion) (p. 314), barbiturates, and   Tenckhoff  catheters;  fluted  T-catheters;   •  Place in dorsal recumbency.
            ethanol                               Blake surgical drains; and Jackson-Pratt   •  Clip,  aseptically  prep,  and  drape  the  area
           •  Hypothermia or hyperthermia         surgical suction drains. Dacron cuffs   from the xiphoid to the pubis.
           •  Resistant metabolic acidosis (severe)  facilitate fibrous attachments, decreasing   •  Administer  cefazolin  25-30 mg/kg  IV  30
                                                  the risk of dialysate leakage and incidence   minutes before PD catheter insertion.
           Contraindications                      of peritonitis.                •  Mini-surgical approach for catheter place-
           •  Peritoneal fibrosis (impaired semipermeable   •  Dialysate solution  ment (author’s preference)
            membrane)                           ○   Commercially prepared dialysate solutions   ○   At  the level  of  the umbilicus,  make a
           •  Pleuroperitoneal  leak  (predisposition  to   are available but often cost-prohibitive.  small  (2-3 cm)  paramedian  skin  and
            iatrogenic pleural effusion)        ○   Homemade solutions using lactated   subcutaneous incision.
           •  Recent  thoracic  or  abdominal  surgery   Ringer’s solution, 0.9% NaCl, or 0.45%   ○   Place  a small  stay  suture  in the  rectus
            (including percutaneous endoscopic gas-  NaCl with dextrose added are more cost-  sheath to facilitate manipulation of the
            trostomy [PEG] tubes)                 effective. Strict aseptic technique (mask   body wall.
           •  Inguinal or abdominal hernia        and sterile gloves) must be followed during   ○   Tent the abdominal wall, and make a small
           •  Severe  hypercatabolic  states  (e.g.,  burn   preparation to reduce contamination.   stab incision into the peritoneum.
            patients)                             Use single-use or new vials when adding   ○   Grasp the PD catheter using a curved
                                                  medication. Wipe all injection ports with   hemostat, and advance the catheter into
           Equipment, Anesthesia                  alcohol before use.                the abdomen toward the pelvic inlet.
           •  General anesthesia (stable patient) or sedation   ○   Add the following to the solution:  Release the catheter, and remove the
            and regional anesthesia (critical patient)  ■   Dextrose to act as an osmotic agent; con-  hemostat.
           •  Clippers                             centration depends on patient’s hydra-  ○   Secure the Dacron cuffs (if present) within
           •  Surgical scrub                       tion status. A 4.5% solution (85 mL    the rectus muscle (inner cuff) and within
           •  #15 scalpel blade                    of 50% dextrose/L) in fluid-overloaded   the subcutaneous tissues (outer cuff) using
           •  Local  anesthetic  (e.g.,  2%  lidocaine  at   patients, whereas a minimum 1.25%   a purse-string suture.
            1-2 mg/kg)                             solution (30 mL of 50% dextrose/L)   ○   Tunnel the distal end of the catheter
           •  Surgical pack                        must be used in normovolemic patients.  through the subcutaneous tissues, and
           •  Suture material                     ■   Unfractionated  heparin  (250  to   exit the skin 2-5 cm away from the
           •  Surgical drapes                      1000 U/L)  for  the  first  few  days  to   abdominal insertion site. If no Dacron
           •  Adhesive dressing (e.g., OpSite)     reduce the risk of catheter obstruction   cuffs are present, begin tunneling under
           •  Closed  Y  connection  system  or  a  3-way   by fibrin clots          the external sheath of the rectus abdominis
            stopcock with one attachment to dialysate   ■   Electrolytes should be added based on   muscle before tunneling subcutaneously.
            line and the other to sterile collection     regular serum electrolyte monitoring.  ○   Before closure, connect the PD catheter to
            system                              ○   Prophylactic antibiotics are not routinely   the dialysate solution in a sterile manner,
           •  Dialysate solution (see below)      added. A one-time loading dose of   and infuse a small volume of dialysate
           •  Peritoneal  dialysis  (PD)  catheter  (see     cefazolin 1000 mg/L of dialysate, followed   (2-5 mL/kg)  into  the  abdomen.  The
            below)                                by a maintenance dose of 250 mg/L of   dialysate  should  flow  by  gravity  into
                                                  dialysate can be added to the dialysate   the collection system if no occlusion is
           Anticipated Time                       solution in cases of suspected peritonitis   present. Redirect if needed until gravity
           Setup: 15 minutes; placement: 30-45 minutes  while awaiting confirmation from cytology   flow occurs.
                                                  and culture.                     ○   Close the entry site through the external
           Preparation: Important                                                    sheath of the rectus abdominis muscle over
           Checkpoints                        Possible Complications and             the PD catheter with a simple interrupted
           •  Drain the urinary bladder before PD catheter   Common Errors to Avoid  pattern using an absorbable monofilament.
            placement to reduce the risk of iatrogenic   Common:                   ○   Close the skin incision with a simple
            puncture.                         •  Dialysate retention (obstruction by omentum   interrupted pattern using non-absorbable
           •  Rehydrate  before  anesthesia,  and  avoid   or fibrin, improper placement, kinking of   monofilament.
            hypotension  to  minimize  further  renal   catheter)                  ○   Secure the catheter to the exit site using
            compromise.                       •  Subcutaneous leakage/limb edema     a purse-string and fingertrap suture.

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