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APUDomas: GI Endocrine Disease                                                  Arrhythmias: ECG Characteristics 1201.e1



            APUDomas: GI Endocrine Disease                       Arrhythmias, Ventricular: Triggers
  VetBooks.ir  Disease          Main Clinical Abnormality         Causes of or Predisposing Factors for Ventricular Arrhythmias



            Glucagonoma         Persistent hyperglycemia; superficial necrolytic   (Premature Ventricular Complexes, Ventricular Tachycardia)
                                                                    Hypokalemia
                                dermatitis (hepatocutaneous syndrome) possible  Hypoxemia (e.g., from pulmonary edema, other causes)
            Gastrinoma          Gastric ulceration                  Anemia
                                                                    Structural heart disease (valvular heart disease, cardiomyopathy, congenital
            Insulinoma          Marked hypoglycemia                   heart disease, others)
            Carcinoids          Carcinoid syndrome as yet unreported in pets  Blunt chest trauma (e.g., hit by car)
            Pancreatic polypeptidoma  Chronic vomiting              Gastric dilation/volvulus
                                                                    Abdominal mass (splenic, hepatic, others)
            Pheochromocytoma    Intermittent catecholamine excess, hypertension  Sepsis
            Somatostatinoma     Diabetes mellitus, cholelithiasis, steatorrhea  Acidosis
            VIPoma              Verner-Morrison syndrome; watery diarrhea  Systemic inflammatory response syndrome (SIRS)
                                                                    Intoxications (digitalis, pseudoephedrine, many other pharmaceuticals;
           APUD, Amine precursor uptake and decarboxylation; GI, gastrointestinal.  oleander, yew, many other plants)
                                                                    Excess catecholamines
                                                                    Myocarditis (diagnosis of exclusion)


            Arrhythmias: ECG Characteristics



            Electrocardiographic Characteristics
                         P Wave                 P Wave                                  QRS          P-QRS            Differentials, Lists,   and Mnemonics
            Rhythm       Rate (bpm)  P-P Interval  Configuration  PR Interval  R-R Interval  Configuration  Relationship
            Sinus        Normal      Constant   Normal         Normal     Constant      Normal       1 : 1
            Sinus bradycardia  <Normal  Constant  Normal       Normal     Constant      Normal       1 : 1
            Sinus tachycardia  >Normal  Constant  Normal       Normal     Constant      Normal       1 : 1
            Sinus arrhythmia  Normal  Variable  Normal or varies   Normal  Variable     Normal       1 : 1
                                                cyclically
            Supraventricular   >Normal  Constant  Positive, negative,   Normal  Constant  Normal     1 : 1
            tachycardia                         absent, or buried
            Atrial flutter  >300     Constant (F-F)  Positive (F waves;   Normal or   Constant or variable   Normal  Generally more
                                                classically, sawtooth   less than P [F]   (if variable, will vary   P [F] waves than
                                                baseline)      wave rate  as a multiple of           QRS complexes
                                                                          P-P [F-F] interval)
            Atrial fibrillation  >500  Variable  None; baseline   None    Variable; ventricular   Normal  No P waves; more
                                                undulation (f waves)      response rate              undulations than
                                                                          typically 100-280/         QRS complexes
                                                                          minute
            Accelerated   Normal     Constant   Normal (often buried   None  Usually constant   Wide  Dissociated; more
            idioventricular                     in QRS complexes)         at 70-160/minute           QRS complexes
            rhythm                                                        (dogs), 110-200            than P waves
                                                                          (cats); rarely
                                                                          irregular
            Ventricular   Normal     Constant   Normal (often buried   None  Constant or    Wide     Dissociated; more
            tachycardia                         in QRS complexes)         irregular at >160/         QRS complexes
                                                                          minute (dogs),             than P waves
                                                                          >200 (cats); can
                                                                          be irregular
            Ventricular flutter  Not discernible  Not discernible  Not discernible  Not discernible  Regular; rate   Sine wave  Dissociated; more
                                                                          >350/minute                QRS waves than P
                                                                                                     waves
            Ventricular   Not discernible  Not discernible  Not discernible  Not discernible  Grossly irregular;   No QRS   Dissociated; no
            fibrillation                                                  rate >400/minute  complexes  QRS complexes
            Second-degree   Normal   Constant   Normal         Constant or   Variable   Normal       More P waves than
            AV block                                           variable*                             QRS complexes
            Third-degree AV   Normal  Constant  Normal         No constant   Constant   Usually wide   Dissociated; more
            block                                              PR interval              (ventricular   P waves than QRS
                                                                                        escape beats)  complexes

           *Gradually lengthens until block, then resets (Mobitz I) or initially constant and then absent when block (Mobitz II).
           Modified from Kittleson M, Kienle RD: Diagnosis and treatment of arrhythmias (dysrhythmias). In: Small animal cardiovascular medicine, St. Louis, 1998, Mosby, p 454.
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