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Neurologic Signs: Brain   1259



            Neurologic Signs: Brain
  VetBooks.ir  Relationship of Clinical Signs to Anatomic Site of Lesion



            Clinical Signs                            Functional System                   Anatomic Location
            Inability to prehend                      Masticatory and tongue muscles      CN V, XII, pons-medulla
            Dysphagia                                 Tongue, palatal, pharyngeal, and esophageal muscles  CN IX, X, XI, XII, medulla
            Drooling                                  Facial paralysis, dysphagia         CN VII, middle ear, medulla
                                                                                          CN IX, X, medulla
            Head tilt, nystagmus, loss of balance, rolling  Vestibular system             CN VIII: inner ear, medulla, cerebellum
            Strabismus                                CN to extraocular muscles, vestibular system  CN III, IV, VI, midbrain-medulla
                                                                                          Inner ear-medulla-cerebellum
            Circling
              With loss of balance                    Vestibular system                   Inner ear, medulla, cerebellum
              Without loss of balance                 Limbic system (?)                   Frontal lobe, rostral thalamus
            Head and eye deviation—turning to one side  Limbic system (?)                 Frontal lobe, rostral thalamus
            Pacing, head pressing                     Limbic system                       Frontal lobe, rostral thalamus
            Opisthotonos                              Upper motor neuron                  Rostral cerebellum, midbrain
            Blindness                                 Visual system
                                                      Dilated unresponsive pupils         Eyeball, optic nerves
                                                      Normal pupils                       Visual cortex–cerebrum (midbrain)
            Depression, semicoma, coma                Ascending reticular activating system  Pons to thalamus–cerebral cortex  Differentials, Lists,   and Mnemonics
            Seizures                                  Cerebrum, thalamus-hypothalamus
            Hyperesthesia, hyperactivity to external stimuli  Ascending reticular activating system  Thalamus, cerebrum
            Aggressive behavior, mania-hysteria, odontoprisis  Limbic system              Thalamus, cerebrum
            Tremor
              Associated with movements, head, and neck  Cerebellar system                Cerebellum
              Associated with movements, head, trunk, limbs  Multiple systems             Diffuse CNS
              Episodic, not associated with movements, head, trunk, limbs                 Thalamus, cerebrum
            Bradycardia, hypothermia, hyperthermia    UMN for general visceral efferent system  Hypothalamus
            Irregular-ataxic respirations             UMN for respiratory muscle LMN      Pons-medulla
           CN, Cranial nerve; CNS, central nervous system; LMN, lower motor neuron; UMN, upper motor neuron; ?, may occur with lesion in this location.
           From de Lahunta A, Glass E: Veterinary neuroanatomy and clinical neurology, ed 3, St. Louis, 2009, Saunders.


































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