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Burns   139


             indicated by examination. Radiographic
             changes in the lungs may progress after
  VetBooks.ir  •  Baseline  aerobic  wound  culture  to  allow                                                        Diseases and   Disorders
             injury.
             targeted antibiotic therapy.
           •  Co-oximetry (if available) to measure car-
             boxyhemoglobin concentrations. Pulse
             oximetry and arterial blood gas analysis may
             provide falsely elevated oxygen levels after
             carbon monoxide exposure.
           Advanced or Confirmatory Testing
           •  Central nervous system imaging (CT, MRI)
             for unexplained alteration in mentation
           •  If pneumonia is suspected, airway lavage for
             appropriate antibiotic selection, assuming
             patient is stable (p. 1073)

            TREATMENT                                      BURNS  A puppy with severe burns after being placed in hot water.
           Treatment Overview
           Goals are to maintain a patent airway and
           oxygenation, support arterial blood pressure   albumin has been associated with severe   tubes are indicated (p. 1107). Concurrent
           and plasma oncotic pressure, maintain adequate   anaphylaxis and death in some dogs.  partial parenteral nutrition can be administered
           urine production, and manage wounds to   ○   Stored or fresh-frozen plasma may be   to achieve full energy requirements.
           prevent tissue loss and reduce risk of infection   considered in patients in need of colloid
           or septic complications. Intravenous fluids,   support who cannot receive synthetic   Behavior/Exercise
           broad-spectrum antimicrobials, and in some   colloids or for secondary coagulopathy   •  For  third-  and  fourth-degree  burns,  espe-
           cases, supplemental oxygen are cornerstones of   (fresh-frozen plasma) (p. 1169).  cially when involving tissues affected by
           treatment.                          •  Oil-based wound dressings (e.g., Vaseline-  motion (e.g., limbs, axilla, inguinal region,
                                                impregnated gauze) should be avoided.  flank),  strict  rest for  3-4 weeks may  be
           Acute General Treatment             •  Third-  and  fourth-degree  burns  may   necessary.
           •  Rapidly cooling burns within 20 minutes   require early escharotomy (debridement)   •  Physical  therapy  or  hydrotherapy  may  be
             of injury is beneficial to prevent ongoing   or fasciotomy to limit wound sepsis and   beneficial to patients with large body surface
             tissue damage. Continuous lavage with cold   compartmentalization.     regions affected.
             (15°C) tap water for 20 minutes is recom-  •  Broad-spectrum  antimicrobial  coverage  if
             mended. Avoid ice.                 evidence of pneumonia until culture results   Possible Complications
           •  Support respiratory function      are available (e.g., ampicillin 22 mg/kg IV   Wound  infection,  pneumonia,  nosocomial
             ○   Oxygen supplementation for patients with   q 8h plus enrofloxacin 10 mg/kg IV q 24h,   infection, sepsis, limb ischemia from wound
               carbon monoxide poisoning from smoke   or 5 mg/kg IV q 24h in cats).  contracture, coagulopathy
               inhalation (pp. 919 and 1146)   •  First- and second-degree burn wounds may
             ○   Maintain airway patency in presence of   require little debridement; application of   Recommended Monitoring
               pharyngeal or laryngeal edema (intubation   antimicrobial topical creams (silver sulfadia-  •  Close initial monitoring of vital parameters
               if necessary) (p. 1166).         zine or 0.5% silver nitrate) is recommended.  •  Arterial blood pressure
             ○   Mechanical ventilation (p. 1185) may be                          •  Quantification of urine production
               required for management of direct lung   Chronic Treatment         •  Oxygen saturation (or ideally co-oximetry)
               injury from inhalation of carbon debris,   •  Small eschars should be debrided for primary   •  Serial  CBC,  serum  biochemistry  profile,
               aspiration pneumonia, or pulmonary   closure early during wound care.  coagulation tests
               edema.                          •  Large  eschars  not  amenable  to  primary
           •  Intensive intravenous (IV) fluid resuscitation   closure should be debrided, allowed to form    PROGNOSIS & OUTCOME
             with crystalloid fluids during the initial 8-12   granulation  tissue,  and  grafted.  Vacuum-
             hours after injury to maintain adequate mean   assisted wound closure (VAC) has been used   •  Outcome  is  generally  good  for  first-  and
             arterial blood pressure and urine production   successfully for large burn wounds. Moist   second-degree burns and guarded for third-
             at 1-2 mL/kg/h. Avoid overhydration and   wound care should be used with open wound   and fourth-degree burns.
             complications secondary to edema (subcu-  management  (e.g.,  manuka  honey  and   •  Prognosis is guarded to poor for moderate
             taneous, pulmonary, cerebral) formation.  nonadherent dressings). Avoid wet-to-dry   to severe inhalation injury.
           •  Systemic  inflammation  and  leaky  vessels   dressings,  which can  delay formation  of   •  Prognosis relies on response to fluid resuscita-
             may  result  in  protein  loss  and  severe   granulation tissue.      tion in severe burn injury. Prognosis improves
             hypoalbuminemia.                  •  Extensive/deep  burns  involving  the  limbs   with appropriate and successful wound
             ○   Judicious use of IV synthetic colloids (e.g.,   should be debrided to avoid limb ischemia   management and worsens with development
               Hetastarch  20 mL/kg/24h,  Vetstarch   and treated with variations of splinting to   of complications.
               20-40 mL/kg/24h) to maintain colloid   avoid contracture.
               oncotic pressure and mean arterial blood                            PEARLS & CONSIDERATIONS
               pressure. Avoid synthetic colloids if there   Nutrition/Diet
               is kidney dysfunction or thrombocytope-  Severe burns cause increased metabolic demand   Comments
               nia (platelet count < 75,000/mcL).  and significant protein losses; early enteral   •  Third-  and  fourth-degree  burns  and/or
             ○   Canine or human albumin may be   nutrition should be instituted. In critically ill   inhalational injuries are best treated in a
               transfused for oncotic pressure. Human   patients, nasoesophageal or nasogastric feeding   tertiary care facility with 24-hour intensive

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