Page 30 - Small Animal Internal Medicine, 6th Edition
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2      PART I   Cardiovascular System Disorders



                   BOX 1.1                                              BOX 1.2
  VetBooks.ir  Clinical Signs of Heart Failure                   Causes of Syncope or Intermittent Weakness

                                                                  Cardiovascular Causes
             Congestive Signs—Left (↑ Left Heart Filling Pressure)
             Pulmonary venous congestion                          Bradyarrhythmias (second- or third-degree AV block,
             Pulmonary edema (causes tachypnea, ↑ respiratory effort,   sinus arrest, sick sinus syndrome, atrial standstill)
               cough, orthopnea, pulmonary crackles, tiring,      Tachyarrhythmias (paroxysmal atrial or ventricular
               cyanosis, hemoptysis)                                tachycardia, reentrant supraventricular tachycardia,
             Postcapillary pulmonary hypertension                   atrial fibrillation)
             Secondary right-sided heart failure                  Congenital ventricular outflow obstruction (pulmonic
             Cardiac arrhythmias                                    stenosis, subaortic stenosis)
                                                                  Acquired ventricular outflow obstruction (heartworm
             Congestive Signs—Right (↑ Right Heart Filling Pressure)  disease and other causes of pulmonary hypertension,
             Systemic venous congestion (causes ↑ central venous    hypertrophic obstructive cardiomyopathy, intracardiac
               pressure, jugular vein distention)                   tumor, thrombus)
             Hepatic ± splenic congestion                         Cyanotic heart disease (tetralogy of Fallot, pulmonary
             Pleural effusion (causes ↑ respiratory effort, orthopnea,   hypertension, and “reversed” shunt)
               cyanosis)                                          Impaired forward cardiac output (severe valvular
             Ascites                                                insufficiency, dilated cardiomyopathy, myocardial
             Small pericardial effusion                             infarction or inflammation)
             Subcutaneous edema                                   Impaired cardiac filling (e.g., cardiac tamponade,
             Cardiac arrhythmias                                    constrictive pericarditis, hypertrophic or restrictive
                                                                    cardiomyopathy, intracardiac tumor, thrombus)
             Low Cardiac Output Signs                             Cardiovascular drugs (diuretics, vasodilators)
             Tiring                                               Neurocardiogenic reflexes (vasovagal, cough-syncope,
             Exertional weakness                                    other situational syncope)
             Syncope
             Prerenal azotemia                                    Pulmonary Causes
             Cyanosis (from poor peripheral circulation)          Diseases causing hypoxemia
             Cardiac arrhythmias                                  Pulmonary hypertension
                                                                  Pulmonary thromboembolism

                                                                  Metabolic and Hematologic Causes
                                                                  Hypoglycemia
                                                                  Hypoadrenocorticism
                                                                  Electrolyte imbalance (especially potassium, calcium)
                                                                  Anemia
                                                                  Sudden hemorrhage
                                                                  Neurologic Causes
                                                                  Cerebrovascular accident
                                                                  Brain tumor
                                                                  (Seizures)
                                                                  Neuromuscular Disease
                                                                  (Narcolepsy, cataplexy)

                                                                 AV, Atrioventricular.
            FIG 1.1
            Syncope in a Doberman Pinscher with paroxysmal
            ventricular tachycardia. Note the extended head and neck
            with stiffened forelimbs. Involuntary micturition also   Tests to explore the cause of intermittent weakness or
            occurred, followed shortly by return of consciousness and   syncope usually include ECG recordings (during rest, exer-
            normal activity.                                     cise, and/or after exercise or a vagal maneuver), complete
                                                                 blood count (CBC), serum biochemical analysis (including
                                                                 electrolytes and glucose), heartworm testing, neurologic
            activity or twitching; however, these convulsive syncopal epi-  examination, thoracic radiographs, and echocardiography.
            sodes are preceded by loss of muscle tone. Presyncope, where   Other studies for neuromuscular or neurologic disease also
            reduced brain perfusion (or substrate delivery) is not severe   may be valuable. Intermittent cardiac arrhythmias that are
            enough to cause unconsciousness, may appear as transient   not apparent on resting ECG may be uncovered by ambula-
            “wobbliness” or weakness, especially in the rear limbs.  tory ECG monitoring, using a 24-hour Holter, event, or
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