Page 472 - Small Animal Internal Medicine, 6th Edition

444 PART III Digestive System Disorders

TABLE 28.7
VetBooks.ir Selected Anthelmintics/Antiprotozoals USE COMMENTS

DRUG
DOSAGE* (PO)
Fenbendazole (Panacur; 50 mg/kg, once daily for 3-5 days H/R/W/G Not approved for cats but often used for
Safe-Guard) 3-5 days in cats to eliminate Giardia.
Give with food.
Metronidazole (Flagyl) 12-15 mg/kg PO q12h for 8 days G Rarely see neurologic signs
(dogs)
17 mg/kg PO q24h for 7 days (cats) Use of metronidazole benzoate is 62%
metronidazole and requires dose of
25 mg/kg
Ronidazole 30 mg/kg PO q24h for 12 days (cats) G For Tritrichomonas infections in cats; drug
(not approved) is not approved for use in animals.
Rarely causes neurologic signs.
Pyrantel (Nemex) 5 mg/kg (dogs) H/R/P Give after meal, repeat in 2 weeks
20 mg/kg, once only (cats) H/R
Pyrantel/febantel/ 10 mg/kg febantel PO in food q24h T/H/R/W Can treat Giardia: q24h for 3 days
praziquantel (Drontal for 3 days (adult dogs and cats)
Plus) 15 mg/kg for puppies and kittens
Imidocloprid/moxidectin Topical—follow manufacturers’ H/R/W
(Advantage multi) recommendations
Ivermectin/Pyrantel Pyrantel 5 mg/kg H/R
(Heartguard plus for Ivermectin 6 µg/kg
dogs)
Milbemycin (Sentinel, 0.5 mg/kg monthly (dog) H/R/W Not approved for use in cats. Not safe to
Trifexis) use in dogs with D. immitis
microfilaremia.
Praziquantel (Droncit) 5 mg/kg PO for dogs > 6.8 kg T 10 mg/kg for juvenile Echinococcus spp.
7.5 mg/kg PO for dogs < 6.8 kg or Spirometra
7.5 mg/kg IM or SC for dogs
< 2.3 kg
6.3 mg/kg IM or SC for dogs
2.7-4.5 kg
5 mg/kg IM or SC for dogs > 5 kg
11.4 mg/cat PO for cats < 1.8 kg; or
IM or SC for cats 1.8-2.2 kg
22.7 mg/cat PO, SC, or IM for cats
2.3-5 kg
34.5 mg/cat PO, IM or SC for cats
> 5 kg
For Heterobilharzia, 20 mg/kg SC
q8h for 1 day (dogs only)
Epsiprantel (Cestex) 5.5 mg/kg PO, once, for dogs T —
2.75 mg/kg PO, once, for cats
Sulfadimethoxine 50 mg/kg on day 1, then C May cause dry eyes, arthritis, various
(Albon) 27.5 mg/kg q12h for 9 days cytopenias, hepatic disease
Trimethoprim- 30 mg/kg for 10 days C May cause dry eyes, arthritis, various
sulfadiazine cytopenias, hepatic disease
(Tribrissen)

C, Coccidia; G, Giardia; H, hookworms; P, Physaloptera; PO, orally; R, roundworms; SC, subcutaneously; T, tapeworms; W, whipworms.
*Dosages are for both dogs and cats unless otherwise specified.