Page 1506 - Veterinary Immunology, 10th Edition

(with CD124), IL-7 (with CD127), IL-9 (with CD129), and IL-15
VetBooks.ir receptors.

CD134 A member of the TNF receptor family that serves as the cell-
binding receptor of feline immunodeficiency virus.

CD140 Platelet-derived growth factor (PDGF) receptor.

CD150 Also called SLAM (signaling lymphocyte activation

molecule). The receptor for canine distemper virus.

CD152 Also known as CTLA-4, this is the ligand for CD80 and
CD86 and a suppressor of T cell activation. It is expressed on
antigen-presenting cells.

CD154 A member of the TNF family. Since it serves as the ligand
for CD40, it is also called CD40L. Found on activated Th cells, it
plays a key role in T cell activation by cross-linking with CD40 on
antigen-presenting cells.

CD158 The KIR family of MHC class I receptors expressed on NK

cells. They play a key role in NK cell activation in primates and
cattle.

CD159 Members of the NKG2 family that serve as inhibitory
receptors on NK cells.

CD166 A leukocyte adhesion molecule that acts as a receptor for IL-

6.

CD169 Siglec-1 or sialoadhesin, a macrophage lectin-like adhesion
molecule.

CD172a A signal regulatory protein expressed on monocytes and a
subset of dendritic cells.

CD178 Also called CD95-L (Fas-ligand). A member of the tumor

necrosis factor superfamily, this is a key molecule in the
induction of cell death by apoptosis.

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