Page 1503 - Veterinary Immunology, 10th Edition

CD71 A transferrin receptor expressed on activated leukocytes. It is
VetBooks.ir required by dividing cells to import iron. It may also act as a

selective IgA receptor.

CD72 Found on B cells (but not plasma cells), CD72 is a ligand for
CD5. It may participate in an alternative pathway of B cell and T

cell activation.

CD74 Also called the γ or invariant chain, this protein associates
with intracellular MHC class II molecules. Found in all MHC
class II–positive cells. It is believed to prevent the premature

binding of endogenous peptides.

CD79 CD79a is an alternative name for the BCR signal-transducing
peptide, Ig-α, and CD79b is another name for Ig-β.

CD80 Also called B7-1, this is high-affinity receptor for CD28 and
CD152 (CTLA-4). The interaction of CD80 with its ligands is

crucial to T cell communication with antigen-presenting cells.

CD81 Also called TAPA-1, CD81 is a widely expressed cell surface
protein that regulates both B cell and T cell responses. On B cells
it forms a complex with CD19 and CD21 and is involved with co-

stimulation of T cells.

CD83 A member of the immunoglobulin superfamily used as a
marker for mature dendritic cells. Its function is unknown.

CD85 A family of leukocyte Ig-like receptors (LIRs) that act as
receptors for MHC class I molecules. They are expressed on
macrophages, dendritic cells, and B cells.

CD86 Related to CD80 and also called B7-2, this co-stimulatory
receptor is expressed on antigen-presenting macrophages,
activated B cells, and dendritic cells. Its ligands are CD28 and
CD152 (CTLA-4).

CD88 The C5a receptor found on granulocytes, macrophages, and

mast cells.

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