Page 1499 - Veterinary Immunology, 10th Edition

CD10 An endopeptidase expressed on T and B cell precursors.
VetBooks.ir CD11 Also called LFA-1, this is an integrin α chain found on

leukocytes. Three forms are known, 11a, 11b, and 11c. They bind
leukocytes to vascular endothelium.

CD14 This is the receptor for lipopolysaccharide-binding protein

and therefore regulates the biological activities of this molecule. It
is found on macrophages and granulocytes.

CD15 A complex carbohydrate called Lewis-X. Its sialylated form,
x
sialyl Lewis , is expressed on NK cells. Its ligand is the selectin
CD62. It is found on many cells, especially granulocytes.

CD16 Also called FcγRIII, this is a low-affinity receptor for IgG and
for CD4. It is found on NK cells, granulocytes, and macrophages.

CD18 This is the integrin β1 chain found on all leukocytes. It
associates with the various forms of CD11. A mutation in the
CD18 gene is responsible for leukocyte adherence deficiency in

calves.

CD19 A protein that associates with CD21 and plays a key role in
regulating the B cell response to antigen. It is expressed on B cells
and their precursors but not on plasma cells. It is also expressed

on dendritic cells.

CD21 A complement receptor also called CR2. Its several ligands
include CD23 and C3d. It regulates B cell responses in association
with CD19. CD21 is found on B cells, some T cells, and dendritic
cells.

CD22 Also called siglec-2; a B cell inhibitory receptor and a receptor
for soluble IgM.

CD23 A receptor for IgE, also called FcεRII. In its soluble form it
regulates the production of IgE. It can also regulate B cell
responses by binding to CD21. It is found mainly on mature B

cells.

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