Page 242 - Canine Lameness
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214  14  Elbow Region

              Early stages of the disease may not be detectable with radiography. If panosteitis is suspected, yet
            no radiographic changes are evident, advanced imaging such as CT or nuclear scintigraphy may be
            utilized. Alternatively, repeat radiographs in two to four weeks in combination with an improve-
            ment in clinical symptoms may verify the diagnosis.


            14.12   Septic Arthritis

            Septic (or infectious) arthritis results from one of three general mechanisms: direct introduction
            (i.e. via surgery or trauma), hematogenous seeding, or local spread of infectious organisms into the
            synovium/joint space. Regardless of the mechanism, the most common cause of infection is bacte-
            rial. However, fungal, protozoal, mycoplasmal, mycobacterial, and rickettsial infections have all
            been reported and should therefore be considered as differential diagnoses particularly if treat-
            ment with antibiotics is unsuccessful. Since lameness associated with septic arthritis requires a
            change of the treatment plan, it is an important differential diagnosis to consider.
              Septic arthritis resulting from direct introduction via surgery is probably the most common form
            of septic arthritis in dogs, yet the incidence is fairly low (approximately 1–5%). The stifle, elbow,
            and carpus have been reported to be most commonly affected.
       ELBOW REGION  dogs. Two different types have been described: a juvenile form in dogs <1 year of age (Fitch
              Hematogenous septic arthritis is likely the second most common form of septic arthritis in

            et  al. 2003) and an adult form, recently also termed “spontaneous septic arthritis,” that is
            described  in  middle-aged  dogs  with  preexisting  joint  disease  (e.g.  osteoarthritis;  Benzioni
            et al. 2008; Mielke et al. 2018). Regardless of the type, in small animals with hematogenous
            septic arthritis, most often a single joint is affected. The juvenile form appears to be rare, but
            large-/giant-breed dogs appear predisposed and the elbow is most frequently affected (Fitch
            et al. 2003). Spontaneous septic arthritis of both the elbow and hip joint has been described
            (Benzioni et al. 2008; Mielke et al. 2018). It is unknown why preexisting joint disease predis -
            poses  to  hematogenous  spread  to  the  joint,  although,  increased  synovial  vascularity/blood
            flow due to chronic osteoarthritis may ease hematogenous introduction of bacteria into the
            joint (Clements et al. 2005).
              Joint infection causes local inflammation followed by release of catabolic enzymes and loss of
            glycosaminoglycan  resulting  in  further  deterioration  of  the  joint.  As  such,  early  intervention
            including at least joint aspiration, culture, and antibiotic therapy should be instituted as soon as
            possible. Other treatment options such as joint irrigation, arthroscopic debridement/lavage, and
            local antibiotics may also be considered.


            14.12.1  Signalment and History
            Most dogs with septic arthritis have a history of surgical intervention, trauma, or previous osteo-
            arthritis in the affected joint. Particularly in the latter case, it can be difficult for owners to dif-
            ferentiate infection from the variable severity of clinical signs associated with osteoarthritis. Dogs
            presenting for septic arthritis after surgery can be of any age and breed. Infection after surgery is
            observed frequently during the early postoperative phase but may also be seen months–years after
            surgery with low-grade infections. Dogs with septic arthritis secondary to chronic osteoarthritis
            are frequently middle-aged to older medium large-breed dogs (Clements et al. 2005; Milgram
            et al. 2018). If acute worsening of a dog with previously diagnosed osteoarthritis is observed,
            spontaneous septic arthritis should be considered an important differential diagnosis.
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