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15  Approach to the Patient with Suspected Cardiovascular Disease     125

               Table 15.2  Simplified table for presumptive diagnosis of murmur origin in common heart conditions
  VetBooks.ir   Point of maximal   Timing  Associated heart conditions  Cause of murmur       Sound quality

                intensity

                Left heart base  Systolic  Physiologic or innocent   Turbulence in aorta/pulmonary   Soft or musical.
                                           murmurs                  artery                    Crescendo‐decrescendo
                                           Aortic and pulmonic stenosis   Turbulence in aorta/pulmonary   Soft to harsh (depending
                                           (tetralogy of Fallot)    artery                    on disease severity).
                                                                                              Crescendo‐decrescendo
                                           Atrial septal defect     Turbulence in pulmonary artery  If present, soft.
                                                                                              Crescendo‐decrescendo
                               Diastolic   Aortic and pulmonic      Turbulence in left or right   Soft, blowing (barely
                                           regurgitation            ventricle                 audible). Decrescendo
                Left axillary   Continuous   Left to right shunting patent   Turbulence in the main   “Machinery” sound of
                region/left heart   (systole and   ductus arteriosus (PDA)  pulmonary artery  varying intensity
                base           diastole)                                                      throughout the cardiac
                                                                                              cycle. Crescendo‐
                                                                                              decrescendo in systole
                                                                                              peaking at S2
                Left heart apex  Systolic  Mitral regurgitation     Turbulence in the left atrium  Soft (blowing), musical,
                                           (secondary to myxomatous                           or harsh, depending on
                                           mitral valve disease, mitral                       disease severity.
                                           dysplasia, etc.)                                   Decrescendo or plateau
                                                                                              shaped
                Right heart    Systolic    Tricuspid regurgitation   Turbulence in the right atrium  Soft to harsh depending
                apex                       (secondary to myxomatous                           on disease severity.
                                           tricuspid valve disease,                           Decrescendo if mild in
                                           tricuspid dysplasia,                               intensity, plateau shaped
                                           pulmonary hypertension, etc.)                      when moderate/severe
                                                                                              in intensity
                Right heart base   Systolic  Ventricular septal defects (left   Turbulence in the right   Harsh and plateau
                (cranially near            to right shunting)       ventricle/right ventricular   shaped (occasionally
                the sternum)                                        outflow tract             varying conformation
                                                                                              throughout systole)
                Parasternal    Systolic    Left ventricular outflow tract   Turbulence in the left ventricular   Soft to harsh,
                (cats)                     obstruction with or without   outflow tract, sometimes   crescendo‐decrescendo
                                           mitral regurgitation     accompanied by turbulence in
                                           (commonly caused by      the left atrium if systolic anterior
                                           hypertrophic cardiomyopathy)  motion (SAM) is present
                               Systolic    Dynamic right ventricular   Turbulence in the right   Soft
                                           outflow tract obstruction   ventricular outflow tract  crescendo‐decrescendo
                                           (DRVOTO) (commonly
                                           stress‐induced or caused by
                                           hemodynamic alterations)


               lung sounds. Auscultation of dogs and cats presenting   can present with interstitial pulmonary edema without
               with pulmonary edema often reveals harsh lung sounds,   any abnormal auscultatory sounds other than increased
               or high‐frequency crackles at the end of inspiration.   bronchovesicular sounds due to hyperpnea.
               Crackles are interrupted, nonmusical, crepitant sounds,   Attenuated or absent bronchovesicular sounds can be
               which in general are associated with conditions in which   due  to  pleural  effusion  or  shallow  breathing.  Animals
               some airways are closed. Crackles should not be consid-  with pleural space disease, such as pleural effusion in
               ered pathognomic for pulmonary edema as primary res-  cats in decompensated CHF, often present with a para-
               piratory disease can also produce crackles. Wheezes,   doxical respiratory pattern with prominent abdominal
               which are high‐frequency musical sounds of longer   wall movements. Thoracic auscultation in these animals
               duration associated with narrowing of an airway, can   may reveal dull lung sounds, muffled heart sounds, or an
               also be heard in animals with pulmonary edema. Animals   auscultable fluid line.
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