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16  Imaging in Cardiovascular Disease  151


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               Figure 16.19  M‐mode echocardiograms obtained from two
               normal dogs at the ventricular level (from the right parasternal
               transventricular short‐axis view, (a)) and the mitral valve level   Figure 16.20  Abnormal M‐mode echocardiograms obtained
               (from the right parasternal transmitral short‐axis view, (b)). (a)   from three cats with heart diseases at the ventricular level (a,b)
               This ventricular M‐mode echocardiogram displays the right   and the mitral valve level (c). (a) In this cat with taurine
               ventricular myocardial wall (RVW) and the right ventricular   deficiency‐induced dilated cardiomyopathy, the ventricular
               cavity (RV) at the top of the image, the left ventricle (LV) and the   M‐mode echocardiogram shows marked dilation of the left
               LV free wall (LVFW) below, with the interventricular septum (IVS)   ventricular cavity (LV) with almost no difference between the
               between the two ventricular cavities. The M‐mode cursor is   end‐diastolic and end‐systolic LV diameters. (b) This ventricular
               placed perpendicular to the IVS and the LVFW between the two   M‐mode echocardiogram in a Maine Coon cat with
               left papillary muscles. The LV end‐diastolic (LVd) and end‐systolic   hypertrophic cardiomyopathy shows severe symmetric
               (LVs) diameters can be measured (double arrows), and the left   hypertrophy (end‐diastolic interventricular septum and LV free
               ventricular fractional shortening (expressed in percentage and   wall >6 mm, double arrows). (c) This M‐mode echocardiogram
               defined as the difference between the LVd and LVs divided by   obtained at the mitral valve level in a cat with hypertrophic
               LVd) can then be calculated. (b) This M‐mode echocardiogram at   cardiomyopathy shows a significant systolic anterior motion of
               the mitral valve level shows the M‐shaped motion of the anterior   the mitral valve (arrows), which is characterized by an
               mitral valve leaflet during diastole. The E point and the smaller A   abnormal mitral valve septal contact during diastole, leading
               point represent the maximum valve opening during the rapid   to LV outflow tract obstruction. IVS, interventricular septum;
               ventricular filling phase and the atrial contraction, respectively.   LVFW, left ventricular free wall.
               Closure of the mitral valve occurs after atrial contraction, at
               end‐diastole.
                                                                  flow across the ventricular septal defect (>5 m/s)
                                                                    associated with normal peak systolic pulmonary flow
                 vascular resistance increases, lower velocities are     velocity is indicative of “restrictive” ventricular septal
               recorded across the ductus.                        shunt, that is, hemodynamically not significant, with
                                                                  conservation of the left ventricle–right ventricle pres-
               Septal Defects (Figures 16.31c and 16.31d)         sure gradient (at least 100 mmHg). Flow velocities
               Color flow Doppler echocardiography associated with   across the atrial septal defect are typically low (<1 m/s),
               spectral Doppler modes may identify small defects that   as the left atrium–right atrium pressure gradient is only
               cannot be visualized on 2D mode images. High‐velocity   several mmHg (Figure 16.31d).
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