Page 2082 - Saunders Comprehensive Review For NCLEX-RN

10. Change the client’s position slowly to prevent
orthostatic hypotension.
11. Monitor for crystallization in the vial of mannitol
before administering the medication; if crystallization
is noted, do not administer the medication from that
vial.

Box 59-1

Antimyasthenic Medications

▪ Edrophonium chloride
▪ Neostigmine bromide
▪ Pyridostigmine

Box 59-2

Signs of Cholinergic Crisis

▪ Abdominal cramps
▪ Nausea, vomiting, and diarrhea
▪ Pupillary miosis
▪ Hypotension and dizziness
▪ Increased bronchial secretions

▪ Increased tearing and salivation
▪ Increased perspiration
▪ Bronchospasm, wheezing, and bradycardia

Box 59-3

Medications for Multiple Sclerosis

Immunomodulators

Interferons (β-1a, 1b, peginterferon β-1a)
Glatiramer acetate
Fingolimod
Teriflunomide
Dimethyl fumarate

Immunosuppressant

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