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Mitoxantrone


               Monoclonal antibodies



                     Natalizumab
                              Alemtuzumab
                              Ocrelizumab


               Potassium channel blockers


                     Dalfampridine (used to improve walking)




               Box 59-4
               Medications to Treat Symptoms of Multiple

               Sclerosis


                  ▪ Bladder and bowel dysfunction: psyllium, docusate

                  ▪ Fatigue: amantadine, modafinil
                  ▪ Depression: fluoxetine, sertraline
                  ▪ Sexual dysfunction: sildenafil, vardenafil
                  ▪ Neuropathic pain: gabapentin, carbamazepine


               Adapted from Burchum JR, Rosenthal LD: Lehne’s pharmacology for nursing care, ed 9.
               St. Louis, 2016, Elsevier.



               Box 59-5

               Medications to Treat Parkinson’s Disease

               Medications Affecting the Amount of Dopamine


                  ▪ Amantadine
                  ▪ Apomorphine
                  ▪ Bromocriptine
                  ▪ Carbidopa-levodopa

                  ▪ Pramipexole
                  ▪ Rasagiline
                  ▪ Ropinirole
                  ▪ Rotigotine
                  ▪ Selegiline hydrochloride




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