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cervical cancer, and genital warts.
                                             2. The vaccine is most effective for boys and girls if
                                                administered before exposure to human
                                                papillomavirus through sexual contact.
                                             3. The vaccine is administered as 3 injections over 6
                                                months—first dose to girls at age 11 to 12 years, the
                                                second dose 2 months after the first dose, and the
                                                third dose 6 months after the first dose.
                                             4. A 3-dose series may be administered to boys 9 to 18
                                                years old to reduce their likelihood of acquiring
                                                genital warts.
                                             5. The vaccine can cause pain, swelling, itching, and
                                                redness at the injection site; fever; nausea; and
                                                dizziness.
                                             6. The vaccine is contraindicated in individuals with a
                                                reaction to a previous injection and in pregnant
                                                women.
                    X. Reactions to a Vaccine
                                A. Local reactions
                                             1. Tenderness, erythema, swelling at injection site
                                             2. Low-grade fever
                                             3. Behavioral changes such as drowsiness, unusual
                                                crying, decreased appetite

                                        B. Minimizing local reactions

                                             1. Select a needle of adequate length to deposit vaccine
                                                deep into the muscle or subcutaneous mass.
                                             2. Inject into the appropriate recommended site.

                                        A. Anaphylactic reactions

                                             1. Goals of treatment are to secure and protect the
                                                airway, restore adequate circulation, and prevent
                                                further exposure to the antigen.
                                             2. For a mild reaction with no evidence of respiratory
                                                distress or cardiovascular compromise, a
                                                subcutaneous injection of an antihistamine, such as
                                                diphenhydramine, and epinephrine may be
                                                administered.
                                             3. For moderate or severe distress, establish an airway;
                                                provide cardiopulmonary resuscitation if the child is
                                                not breathing; elevate the head; administer
                                                epinephrine, fluids, and vasopressors as prescribed;
                                                monitor vital signs; and monitor urine output.
                                B. Refer to Chapter 62 for additional information on allergic
                                   responses and anaphylactic reactions
                    XI. Developmental Characteristics
                                A. Infant




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