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        254             A Glossary for Design of Experiments with Examples
                                 Shewhart c  Constant vs Sub-Group Size
                                         4
                       12
                       10
                      Shewhart c 4  Constant  08
                       06

                       04
                       02

                       00
                          0       5       10       15       20      25
                                          Sub-Group Size

            Figure 16.13 Graphical illustration of Shewhart c 4 constant vs. the subgroup size.


        for F(α = 0.05, 1,ν e ) distributions. From Figure 16.14 it may be observed that the
        significance of an effect will be difficult to prove for ν e of 3 or less, while there is little
        cause for concern for ν e of 15 and above.
               k
          In a 2 factorial experiment, there will be k degrees of freedom for the main effects
        and / 2k(k−1) degrees of freedom for the two-way interactions. With r replicates, there
            1
                 k
        will be r(2 −1) total degrees of freedom for the design.
          Consider the example in Table 16.9 with three control factors and three noise factors
        (and four blocks); the effect of replicates an confounding is shown in Table 16.12. For
        two replicates, the blocks are confounded with the three-way interaction ABC. If
        time and/or cost is a constraint and one is confident that the ABC interaction is not
        practically significant, then two replicates may be adequate in identifying significant



                              Critical Values for FDIST (α = 0.05, n  = 1, n  = ν)
                                                             2
                                                        1
                     20
                     16

                    F-Critical  12 8




                      4

                      0
                        0      5       10     15      20      25      30
                                        Degrees of Freedom
                    Figure 16.14 Graph of critical F-values vs. degrees of freedom.
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