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 JWBK119-19
                                  Possible Applications                      303
      Table 19.3 Results of lean designs in incremental experimentation.
      Estimated effect   L 6 2 7−4  y 7 , y 8 absent  L 7 2 7−4  y 8 absent  2 7−4  Regular data set
      l 1                    −11.40              −11.40              −10.875
      l 2                       0.65              −3.30               −2.775
      l 3                    −13.15              −17.10              −16.575
      l 4                       2.65               2.65                3.175
      l 5                    −23.35              −23.35              −22.825
      l 6                       0                 −3.95               −3.425
      l 7                       0                  0                   0.525


        Another possible lean design is one with seven experimental runs, or L 7 2 7−4 . In this
      case only one factor needs to be assumed unimportant. If x 7 is such a factor and y 8 is
      unavailable, then one can set
            1
        l 7 =  (−y 1 + y 2 + y 3 − y 4 + y 5 − y 6 − y 7 + ˆy 8 ) = 0.     (19.9)
            4
      Hence
        ˆ y 8 = y 1 − y 2 − y 3 + y 4 − y 5 + y 6 + y 7 = 36.6,           (19.10)
      with which all the other l i values can be computed.
        The results of analysis of the above two lean designs are exhibited in Table 19.3,
      along with the results obtained from the full 2 7−4  experimental data from the filtration
      study. It is evident from the table that, using an L 6 2 7−4  design, the investigator would
      arrive at exactly the same four tentative conclusions associated with the data from
                                           6
      the regular 2 7−4  design (p. 426 of Box et al. ). With one more experimental run -- that
      is, with an L 7 2 7−4  design -- there would still be no change in the interpretation. This
      shows, in a striking manner, that with a considerably smaller amount of experimental
      effort, lean design works extremely well when the investigator is able to make a good
      prior judgment concerning the relative importance -- or rather, unimportance -- of the
      factors under study.
        Even if the judgment of the investigator is somewhat off the mark, especially in
      the presence of unsuspected interactions, the results of a lean design can still be
      gradually improved upon by the addition of one further experimental run at a time.
      Thus the filtration plant study can start with a lean design of L 6 2 7−4  to obtain some
      provisional findings, followed by the generation of response y 7 to produce the results
      corresponding to an L 7 2 7−4  design, and finally y 8 to arrive at what a regular 2 7−4
      design can reveal about the plant behavior. Such an incremental experimentation or one-
      additional-run-at-a-time scheme, has the same merit as that advocated for sequential
      fold-over designs, namely earlier availability of first results, and improvement of such
      results as new data becomes available.


                          19.6  POSSIBLE APPLICATIONS
      Lean design is useful in circumstances such as those described below.

      1. It is imperative to have only the minimum number of experimental runs in view
        of, for example, expensive prototypes, high costs of destructive tests, or costly
        disruptions to regular production.
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