Page 224 - The Manga Guide to Biochemistry
P. 224
T 5´ P
4´
1´
2´ 3´
5´ A 1´ 4´
4´ 2´ 3´
1´
3´ 2´ P 5´ A
P 5´ T 1´ 4´
2´ 3´
4´ 1´ 5´ G P
3´ 2´
P 5´ C C 5´
4´
If the two 4´ 1´ 1´
2´ 2´ 3´
combs are 3´ 5´
joined...
...and P G
twisted
...we 4´ 1´
get into a 3´ 2´
DNA! helix...
Oh! Those comb-teeth-looking parts stick together and become the rungs in
the middle!
Right. In other words, a “pair” is created via hydrogen bonds between two
bases, so that the polynucleotides form a double strand. The pairings are
always faithful: A pairs with T (with two hydrogen bonds), and G pairs with C
(with three hydrogen bonds).
Always these
combinations
AG
Hydrogen
bond
TC
210 Chapter 5
