Page 55 - Children Bookt.pdf

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Preferred second-line regimen
Quality
First-line regimen RTI components PI Strength of
of
at failure (NRTI/NNRTI) a component recommendation
evidence
2 NRTIs +
ABC + 3TC
++!* Moderate
or LPV/r d Strong
AZT- or d4T-
ABC + ddI
containing plus
AZT + 3TC
or
or
ABC-containing
AZT + ddI LPV/r d Strong High
ddI + EFVc or
d
Triple NRTI
NVP
(a) Continuation of 3TC in second-line regimens may be considered.
(b) ddI may not need to be taken on an empty stomach in children.
(c) EFV is currently not recommended for children <3 years of age, and should be
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(d) LPV/r is available as solid and liquid co-formulations.

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