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5. Minor RNA t mvB‡UvcøvRgxq RNA I wbDK¬xq RNA bv‡g wKQz ¶z`ª RNA i‡q‡Q, hviv †Kv‡l wewfbœ †cÖvwU‡bi mv‡_
wg‡k GbRvB‡gi KvVv‡gv cÖ`vb K‡i| G RvZxq wKQy RNA i g‡a¨ GbRvB‡gi ˆewkó¨ _vKvq G¸‡jv‡K ivB‡evRvBg
bv‡g AwfwnZ Kiv nq, †hgb- ivB‡evwbDwK¬q †cÖvwUb|
15| DNA AYyi wØZb ev cÖwZiyc m„wó (Replication of DNA ) eY©bv Ki|
DNA AYyi wØZb ev cÖwZiyc m„wó (Replication of DNA ) t †h cÖwµqvq
GKwU DNA Wvej †nwj· n‡Z c~e©vbyiyc `ywU AYyi m„wó K‡i ,Zv‡K DNA AYyi
wØZb ev cÖwZiyc m„wó e‡j| B›Uvi‡dR ch©v‡q DNA Zvi cÖwZiyc m„wó K‡i| DNA
i cÖwZiyc m„wó wb‡gœv³ avc¸‡jvi gva¨‡g AwZ `ªyZ, Awew”Qbœ I wbLuyZfv‡e m¤úbœ
nq-
1) nvB‡Wªv‡Rb e‡Ûi we‡jvc mvab t wØZ‡bi cÖv_wgK ch©v‡q wcDwib I
cvBwiwgwWb †e‡mi ms‡hvM mvabKvix nvB‡Wªv‡Rb eÛ †f‡½ hvq| d‡j DNA AYyi
GKvsk ci¯úi †_‡K c„_K n‡q c‡o Ges cÖwZwU †nwj· QuvP wn‡m‡e Kvh©Kix nq|
wkKj c„_K Kivi †¶‡Î DNA †nwj‡KR GbRvBg mnvqZv K‡i|
2) m¤úyiK m„wó t ci¯úi †_‡K c„_K nIqvi ci †nwj· ev m~Î`ywU Quv‡Pi g‡Zv
KvR K‡i| bZzb †nwj· ˆZwii Rb¨ cÖ‡qvRbxq Dcv`vb A_©vr kK©iv, †em I
dm‡dU h_vmg‡q h_v¯’v‡b Dcw¯’Z nq Ges m¤úyiK m~Î m„wó nq| m¤úyiK m„wói
Rb¨ Aek¨ DNA cwjgv‡iR GbRvBg Ges g¨vM‡bwmqvg Avq‡bi Dcw¯’wZ cÖ‡qvRb
nq| bZzb †nwj‡·i GKwU me mgqB 5©→3© AwfgyLx e„w× cvq| G‡K AMÖMvgx
m~ÎK (leading stand ) e‡j| Aci m~ÎKwU 3©→5© AwfgyLx e„w× cvq | G‡K
wcwQ‡q cov m~ÎK (lagging stand) e‡j|
3) Quv‡Pi †e‡mi Abyµg Abymv‡i m¤úyiK †e‡mi web¨vm I nvB‡Wªv‡Rb e‡Ûi m„wó t bZzb
m„ó m~Î`ywU‡Z Quv‡Pi †em Gi Abyµg Abymv‡i †em¸‡jv web¨¯Í n‡Z _v‡K| A_©vr Quv‡P hw`
A¨v‡Wwbb _v‡K Z‡e Zvi wecix‡Z m„ó bZzb m~ÎwU‡Z _vBwgb ms‡hvwRZ nq| Abyi~cfv‡e
wØZxq Quv‡P mvB‡Uvwmb _vK‡j Zvi wecix‡Z m„ó bZzb m~‡Î m¤ú~iK †em wn‡m‡e ¸qvwbb
ms‡hvwRZ nq| AZtci Quv‡Pi I bZzb m„ó m¤ú~iK †e‡mi g‡a¨ cybivq nvB‡Wªv‡Rb e‡Ûi
Avwef©ve n‡j GKwU DNA AYy †_‡K `ywU DNA AYyi m„wó nq|
¸iæZ¡c~Y© Z_¨ t DNA Abywjcb c×wZ wZb cÖKv‡ii n‡q _v‡K Ñ
1. Aa©msi¶Ykxj ev Semiconservative Abywjcb g‡Wj t G ai‡bi Abywjcb c×wZ‡Z AcZ¨ DNA w؇nwj‡·i
GKwU m~Î gvZ… DNA †_‡K cvIqv hv‡e Ges G‡K †Ug‡cøU wn‡m‡e e¨envi K‡i cwic~iK m~‡Îi ms‡kølY NU‡e|
2. msi¶Ykxj ev conservative Abywjcb g‡Wj t G c×wZ Abymv‡i Abywjc‡bi mgq gvZ… DNA AYywU AweK…Z
Ae¯’vq QuvP wn‡m‡e KvR K‡i Ges m¤ú~Y©fv‡e c„_K wKš‘ cwic~iK AcZ¨ DNA AYy Drcbœ Ki‡e|
3. we”QyiYkxj ev Dispersive Replication Model t G c×wZ Abymv‡i DNA AYy Abywjc‡bi mgq gvZ… DNA
AYyi m~ÎØq †QvU †QvU L‡Û †f‡O hvq| Gici gvZ… DNA L‡Ûi gv‡S gv‡S AcZ¨ DNA LÛ hy³ n‡q c~Y©v½ DNA
AYy MVb K‡i|
DNA AYywjc‡bi Rb¨ cÖ‡qvRbxq GbRvBgmg~n t DNA AYywjc‡bi Rb¨ wewfbœ ch©v‡q cÖvq 30 ai‡bi GbRvB‡gi
cÖ‡qvRb c‡o| wb‡P cÖavb K‡qKwU GbRvB‡gi KvR D‡jøL Kiv n‡jv -
GbRvBg KvR
1. †nwj‡KR DNA ‡nwj‡·i cwic~iK †PB‡bi nvB‡Wªv‡Rb e×bx †f‡O m~Î c„_K K‡i|
2. cÖvB‡gR DNA cÖvBgvi hy³ K‡i|
3. cwjgv‡iR-III DNA ‡PB‡b bvB‡Uªv‡Rb ¶viK hy³ K‡i I GwU ms‡kvab K‡i|
4. cwjgv‡iR-I cÖvBgvi RNA mwi‡q †bq|
mbRq P›`ª gÛj, mnKvwi Aa¨vcK, Dw™¢` weÁvb wefvM, RqcyinvU miKvwi K‡jR, RqcyinvU| sanjoymondal1980@gmail.com Mob- 01713747235 12