Page 14 - Botany

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mRNA cÖwµqvKiY t †`Lv †M‡Q †h AwaKvsk cÖK…Z‡Kvlx Rx‡e (†hgb ¯Íb¨cvqx ) wmmUª‡bi †h Ask †_‡K mRNA Z_¨ MÖnb
K‡i Zvi GK cÂgvsk wbDwK¬IUvBW web¨vmB †cÖvwU‡bi †Kvb ms‡KZ enb K‡i bv| Giƒc ms‡KZwenxb Ask‡K BbUªb (Intron )
Ges ms‡KZevnx Ask‡K G·b (Exon ) e‡j| wbDwK¬qvm †_‡K †ei n‡q mvB‡UvcøvR‡g cÖ‡e‡ki Av‡M BbUªb Ask¸‡jv ev` w`‡q
G·b Ask¸‡jv cybtms‡hvwRZ n‡q Kvh©Kix mRNA MVb K‡i| Gfv‡e G·b As‡ki cybwe©b¨vm wRb ¯úøvBwms (Splicing)

wn‡m‡e cwiwPZ| 5©- cÖv‡šÍ GTP cap Ges 3©- cÖv‡šÍ cwj A¨v‡Wwbb Gi †jR ˆZix nIqvi ci Kvh©Kix mRNA wbDwK¬qvm †_‡K
†ei nq Ges ivB‡ev‡mv‡gi mv‡_ hy³ n‡q cwj‡ccUvBW ms‡køl K‡i|

17| Uªv݇jkb ej‡Z Kx †evS? cÖwµqvwU e¨vL¨v Ki|
Uªv݇jkY (Translation ) t †h cÖwµqvq mRNA KZ©„K evwnZ †R‡bwUK †KvW ivB‡ev‡mv‡g tRNA Gi mvnv‡h¨ A¨vwg‡bv
A¨vwmW mgš^‡q cwj‡ccUvBW Z_v †cÖvwUb ms‡køl wb‡`©k K‡i Zv‡K Uªv݇jkb e‡j| Uªv݇jkb cÖwµqvwU wb‡æv³fv‡e m¤úbœ n‡q
_v‡K-
1. ivB‡ev‡mvg Gi mv‡_ mRNA Gi mshyw³ t UªvÝwµckb cÖwµqvq m„ó mRNA wbDwK¬qvm †_‡K gy³ n‡q mvB‡UvcøvR‡g
we`¨gvb ivB‡ev‡mv‡gi †QvU GK‡Ki mv‡_ hy³ nq Ges G ¯’v‡b †KvWb I Gw›U‡KvWb Gi wgjb N‡U| †cÖvwUb ms‡kø‡li
c~‡e© ivB‡ev‡mvg¸‡jv wbw®Œq _v‡K Ges G‡`i DcGKK¸‡jv c„_K c„_Kfv‡e _v‡K| †cÖvwUb ms‡kølKv‡j ivB‡ev‡mv‡gi

Dc GKKØq hy³ n‡q 80S I 70S ivB‡ev‡mvg m„wó K‡i| GKwU mRNA i mv‡_ GKvwaK ivB‡ev‡mvg hy³ _vKvq
G‡`i‡K cwjivB‡ev‡mvg ev cwj‡mvg e‡j|
2. A¨vwg‡bv A¨vwmW Gi mwµqZv t mvB‡UvcøvR‡g we`¨gvb A¨vwg‡bv A¨vwmW¸‡jv tRNA Øviv hy³ nevi hy³ nevi c~‡e©
++
ATP i Dcw¯’wZ‡Z mwµq nq| A¨vwg‡bv A¨vmvBj tRNA wm‡š’‡UR bvgK GbRvBg I Mg Gi Dcw¯’wZ‡Z A¨vwg‡bv
A¨vwmW¸‡jv A¨vwg‡bv A¨vmvBj A¨vwW‡bvwmb g‡bvdm‡dU I cvB‡ivdm‡dU ˆZwi K‡i|
A¨vwg‡bv A¨vmvBj tRNA wm‡š’‡UR
A¨vwg‡bv A¨vwmW + ATP ----------------------------→ A¨vwg‡bv A¨vmvBj A¨vwW‡bvwmb g‡bvdm‡dU + cvB‡ivdm‡dU
3. A¨vwg‡bv A¨vwmW Gi mwµqZv Ges tRNA Gi mshyw³ t GLb mwµq A¨vwg‡bv A¨vwmW tRNA Gi mv‡_ hy³ n‡q
A¨vwg‡bv A¨vmvBj tRNA ‰Zwi K‡i Ges GbRvBg gy³ K‡i|

A¨vwg‡bv A¨vmvBj tRNA wm‡š’‡UR
A¨vwg‡bv A¨vmvBj A¨vwW‡bvwmb g‡bvdm‡dU + tRNA ----------------------------→ A¨vwg‡bv A¨vmvBj tRNA + AMP + enzyme
4. †cÖvwUb ms‡kølY Gi m~Pbv t Avw`‡Kvl I fvBiv‡mi †¶‡Î mRNA i AUG ‡KvWb Uªv݇jk‡bi m~Pbv K‡i| D³
†KvWb digvBj ‡gw_Iwbb tRNA (f met-tRNA ) ‡K hy&³ K‡i| cÖK…Z †Kvlx Rx‡ei †¶‡Î f met-tRNA Gi
cwie‡Z© met-tRNA cÖ_‡g mRNA Gi †KvW‡bi mv‡_ hy³ nq|

mbRq P›`ª gÛj, mnKvwi Aa¨vcK, Dw™¢` weÁvb wefvM, RqcyinvU miKvwi K‡jR, RqcyinvU| sanjoymondal1980@gmail.com Mob- 01713747235 14