Page 1208 - Basic _ Clinical Pharmacology ( PDFDrive )
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1194     Index


                 Bactericidal activity, 910, 910t  Benzene hexachlorides, 1010t, 1010–1011,   monobactams, 796f, 806, 812t
                 Bacteriostatic activity, 910, 910t        1013f                        penicillins, 795–801, 812t
                 Bagging, 585                      Benznidazole, 933t, 934              preparations available, 813t
                 Balanced anesthesia, 440, 449     Benzocaine. See also Anesthetics, local  Betamethasone, 706f, 709t. See also
                 Balanced polyethylene glycol, 1099  description of, 460t, 470, 472t          Corticosteroids, synthetic
                 Ballismus, 492, 505                 in OTC agents, 1129t             b-receptor agonist drugs, 225t
                 Balsalazide, 1107, 1107f          Benzodiazepines, 393t              b-receptor antagonist drugs
                 Bambuterol, 351                     abuse of, 577t                     angina pectoris treated with, 194,
                 Bapineuzumab, 1063                  acute ethanol withdrawal managed with,   206–207, 210t
                 Barbiturates, 393t                        406t, 585, 589t                with nitrates, 208, 209t
                   anesthesia uses of, 442f, 450t, 451f,   anesthesia uses of, 389, 451f, 454–455  arrhythmias treated with, 168, 243,
                        453–454                      antagonists of, 390, 393t                250t, 251t
                   biotransformation of, 386         antiemetic properties of, 1106     choice of, 169
                   chemical classification of, 382, 383f  anxiety managed with, 544     clinical pharmacology of, 167–169
                   clinical pharmacology of, 390t    binding site ligands of, 387–388     cardiac arrhythmias, 168
                   dose-response curves for, 381, 382f  biotransformation of, 383–386, 384f,   cardiovascular disorders, other, 168
                   drug interactions of, 1160t             385t                           glaucoma, 168
                   neuropharmacology of, 386–387     chemical classification of, 381–383, 382f  heart failure, 168
                   pharmacodynamics of, 386–389      clinical pharmacology of, 390t, 390–391  hypertension, 167
                   pharmacokinetics of               disadvantages of, 390                hyperthyroidism, 168
                    absorption and distribution in, 386  dose-response curves for, 381, 382f  ischemic heart disease, 167f, 167–168,
                    biodisposition in, factors in, 386  epilepsy managed with, 432, 437t      168f
                    excretion in, 386                flumazenil reversal of, 392          miscellaneous, 169
                   structure of, 383f                ionotropic receptors in, 584         neurologic diseases, 168–169
                 Baroreceptor, renal, 301            pharmacodynamics of, 386–389       drug interactions of, 1161t
                 Baroreflex, postural, 175, 175f     pharmacokinetics of                heart failure treated with, 221
                 Bartter’s syndrome, 335               absorption and distribution in, 386  chronic, 222
                 Bases, weak                           biodisposition in, 386             dobutamine, 219
                   definition of, 9                    excretion in, 386                  preparations available, 226t
                   examples of, 10t                  structure of, 382f                 hypertension treated with, 179t,
                   ionization of, 9                Benzoic acid, 901                          182–183, 192t
                   trapping of, 9, 11f             Benzomorphans, 569                     esmolol, 183
                 Basic research, 14b               Benzophenones, 1076                    labetalol, carvedilol, and nebivolol,
                 Basiliximab, 994                  Benzoyl peroxide, 1078                     183, 192t
                 Batrachotoxin, 370t               Benztropine, 126f                      metoprolol and atenolol, 179t, 183
                 Bazedoxifene, 737f, 738           Benztropine mesylate, 501t, 508t       nadolol, carteolol, betaxolol, and
                 BCNU (carmustine), 953f           Benzyl alcohol, 1076                       bisoprolol, 183
                 Beclomethasone (dipropionate), 355, 362t.   Bepridil, 204. See also Calcium channel   pindolol, acebutolol, and penbutolol,
                        See also Corticosteroids, inhaled   blockers                          183
                        (aerosol)                  Berinert. See also Kinin inhibitors    propranolol, 179t, 182–183
                 Bedaquiline, 843t, 849              description of, 308, 317t          hyperthyroidism treated with, 696, 698,
                 Beef tapeworms                      on vasoactive peptides, 317t             700, 701t
                   niclosamide for, 943            Beryllium, 1017                      as inverse agonists, 162
                   praziquantel for, 944–945       b adrenoceptor, 139t, 139–140, 140f  latanoprost and related agents, 337
                 Belimumab, 658, 994                 affinities of, 141, 141t           pharmacodynamics of, 162–165
                 Benazepril, 179t, 187               cardiovascular system activation by, 145,   on cardiovascular system, 162–163,
                 Bendamustine, 955t                        146f, 146t, 147                    164f
                 Benign hereditary chorea, 505     b-arrestin, 32, 33f                    on eye, 164
                 Benign prostate hyperplasia (BPH)  Beta blockers, 162. See b-receptor antagonist   for glaucoma, 165b, 166t
                   alpha-receptor antagonists for,         drugs                          metabolic and endocrine effects in,
                        159, 161                   Beta-lactamase assay, 906                  164–165
                   saw palmetto for, 1141          Beta-lactamase inhibitors, 806f, 806–807  non–beta-blockade effects in, 164t,
                 Benralizumab, 357, 363t           Beta-lactam compounds, 795–807,            165
                 Benzalkonium chloride, 900                812t–813t. See also specific types  on respiratory tract, 163–164
                 Benzamides, substituted, 1106       beta-lactamase inhibitors, 806f, 806–807  pharmacokinetics of, 162, 164t
                 Benzathine penicillin, 799. See also   carbapenems, 796f, 807, 812t    poisoning management for, 1041t, 1043
                        Penicillin(s)                cephalosporins and cephamycins, 796f,   preparations available, 171t
                 Benzene, 1009–1010                        802–806, 812t                  hypertension treated with, 193t
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