Page 1208 - Basic _ Clinical Pharmacology ( PDFDrive )
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1194 Index
Bactericidal activity, 910, 910t Benzene hexachlorides, 1010t, 1010–1011, monobactams, 796f, 806, 812t
Bacteriostatic activity, 910, 910t 1013f penicillins, 795–801, 812t
Bagging, 585 Benznidazole, 933t, 934 preparations available, 813t
Balanced anesthesia, 440, 449 Benzocaine. See also Anesthetics, local Betamethasone, 706f, 709t. See also
Balanced polyethylene glycol, 1099 description of, 460t, 470, 472t Corticosteroids, synthetic
Ballismus, 492, 505 in OTC agents, 1129t b-receptor agonist drugs, 225t
Balsalazide, 1107, 1107f Benzodiazepines, 393t b-receptor antagonist drugs
Bambuterol, 351 abuse of, 577t angina pectoris treated with, 194,
Bapineuzumab, 1063 acute ethanol withdrawal managed with, 206–207, 210t
Barbiturates, 393t 406t, 585, 589t with nitrates, 208, 209t
anesthesia uses of, 442f, 450t, 451f, anesthesia uses of, 389, 451f, 454–455 arrhythmias treated with, 168, 243,
453–454 antagonists of, 390, 393t 250t, 251t
biotransformation of, 386 antiemetic properties of, 1106 choice of, 169
chemical classification of, 382, 383f anxiety managed with, 544 clinical pharmacology of, 167–169
clinical pharmacology of, 390t binding site ligands of, 387–388 cardiac arrhythmias, 168
dose-response curves for, 381, 382f biotransformation of, 383–386, 384f, cardiovascular disorders, other, 168
drug interactions of, 1160t 385t glaucoma, 168
neuropharmacology of, 386–387 chemical classification of, 381–383, 382f heart failure, 168
pharmacodynamics of, 386–389 clinical pharmacology of, 390t, 390–391 hypertension, 167
pharmacokinetics of disadvantages of, 390 hyperthyroidism, 168
absorption and distribution in, 386 dose-response curves for, 381, 382f ischemic heart disease, 167f, 167–168,
biodisposition in, factors in, 386 epilepsy managed with, 432, 437t 168f
excretion in, 386 flumazenil reversal of, 392 miscellaneous, 169
structure of, 383f ionotropic receptors in, 584 neurologic diseases, 168–169
Baroreceptor, renal, 301 pharmacodynamics of, 386–389 drug interactions of, 1161t
Baroreflex, postural, 175, 175f pharmacokinetics of heart failure treated with, 221
Bartter’s syndrome, 335 absorption and distribution in, 386 chronic, 222
Bases, weak biodisposition in, 386 dobutamine, 219
definition of, 9 excretion in, 386 preparations available, 226t
examples of, 10t structure of, 382f hypertension treated with, 179t,
ionization of, 9 Benzoic acid, 901 182–183, 192t
trapping of, 9, 11f Benzomorphans, 569 esmolol, 183
Basic research, 14b Benzophenones, 1076 labetalol, carvedilol, and nebivolol,
Basiliximab, 994 Benzoyl peroxide, 1078 183, 192t
Batrachotoxin, 370t Benztropine, 126f metoprolol and atenolol, 179t, 183
Bazedoxifene, 737f, 738 Benztropine mesylate, 501t, 508t nadolol, carteolol, betaxolol, and
BCNU (carmustine), 953f Benzyl alcohol, 1076 bisoprolol, 183
Beclomethasone (dipropionate), 355, 362t. Bepridil, 204. See also Calcium channel pindolol, acebutolol, and penbutolol,
See also Corticosteroids, inhaled blockers 183
(aerosol) Berinert. See also Kinin inhibitors propranolol, 179t, 182–183
Bedaquiline, 843t, 849 description of, 308, 317t hyperthyroidism treated with, 696, 698,
Beef tapeworms on vasoactive peptides, 317t 700, 701t
niclosamide for, 943 Beryllium, 1017 as inverse agonists, 162
praziquantel for, 944–945 b adrenoceptor, 139t, 139–140, 140f latanoprost and related agents, 337
Belimumab, 658, 994 affinities of, 141, 141t pharmacodynamics of, 162–165
Benazepril, 179t, 187 cardiovascular system activation by, 145, on cardiovascular system, 162–163,
Bendamustine, 955t 146f, 146t, 147 164f
Benign hereditary chorea, 505 b-arrestin, 32, 33f on eye, 164
Benign prostate hyperplasia (BPH) Beta blockers, 162. See b-receptor antagonist for glaucoma, 165b, 166t
alpha-receptor antagonists for, drugs metabolic and endocrine effects in,
159, 161 Beta-lactamase assay, 906 164–165
saw palmetto for, 1141 Beta-lactamase inhibitors, 806f, 806–807 non–beta-blockade effects in, 164t,
Benralizumab, 357, 363t Beta-lactam compounds, 795–807, 165
Benzalkonium chloride, 900 812t–813t. See also specific types on respiratory tract, 163–164
Benzamides, substituted, 1106 beta-lactamase inhibitors, 806f, 806–807 pharmacokinetics of, 162, 164t
Benzathine penicillin, 799. See also carbapenems, 796f, 807, 812t poisoning management for, 1041t, 1043
Penicillin(s) cephalosporins and cephamycins, 796f, preparations available, 171t
Benzene, 1009–1010 802–806, 812t hypertension treated with, 193t