Page 1213 - Basic _ Clinical Pharmacology ( PDFDrive )

Index 1199

antipsychotics and antidepressants, Charcoal, activated, 1040 imatinib and other tyrosine kinase
1061–1062 Chart orders, 1147. See also Prescriptions inhibitors, 966t, 967
sedative-hypnotics, 1061 abbreviations in, 1149t leukemia, acute
Central nervous system (CNS) neurotrans- errors of omission in, 1149–1150 adult, 969
mitters, 375–380 Charybdotoxin, 370t childhood, 969
acetylcholine, 374f, 376t, 378 Chelators, 1029–1033. See also specific types leukemia, chronic
amino acid, 375–378 deferasirox, 1032–1033 lymphocytic, 970
GABA and glycine, 376t, 378 deferoxamine, 1032 myelogenous, 969–970
glutamate, 375, 376t, 377f dimercaprol, 1024, 1026, 1029, 1030, lymphoma
endocannabinoids, 377t, 379–380 1030f Hodgkin’s, 970
monoamine edetate calcium disodium, 1023, 1029f, non-Hodgkin’s, 970
dopamine, 374f, 376t, 378 1031 malignant melanoma, 974–975
histamine, 376t, 379 penicillamine, 1030f, 1032 multiple myeloma, 970–971
5-hydroxytryptamine, 374f, 376t, 379 pharmacology of, 1029f, 1029–1030 natural product drugs, 961–964, 962t
norepinephrine, 374f, 376t, 378–379 preparations available, 1033t camptothecins, 962t, 964
neuropeptides, 379 Prussian blue, 1033 epidophyllotoxins, 962t, 964
nitric oxide, 380 succimer, 1024, 1027, 1029, 1030f, taxanes and other anti-microtubule
opioid peptides, 377t 1030–1031 drugs, 962t, 963–964
orexins, 377t, 379 unithiol, 1026–1027, 1031–1032 vinca alkaloids, 961–962, 962t
purine, 380 Chemical antagonism, 25 neoadjuvant, 949–950
tachykinins, 377t Chemical antagonist, 3 ovarian cancer, 974
Cephalexin, 802f, 803t Chemical transmission, 89–90. See also primary, 949
Cephalosporins, 796f, 802–806, 812t Neurotransmitters prostate cancer, 972
adverse effects of, 806 Chemoattractant cytokines (chemokines), secondary malignancies, 975
chemistry and structure of, 796f, 802, 978 testicular cancer, 974
802f Chemokines, 978 Chemotherapy-induced nausea and
dosing of, 803t Chemoreceptor reflex, 287 vomiting, 1104, 1116t, 1117t
first-generation, 802f, 802–804, 803t Chemoreceptor trigger zone, 1103, 1104f Chemotherapy-induced neutropenia,
fourth-generation, 802f, 803t, 805–806 Chemotherapy, 948–976. See also specific G-CSF for, 603, 603f, 606t
methicillin-resistant staphylococci treated drugs Chimeric molecules, 990
with, 802f, 803t, 804–806 adjuvant, 950 Chirality, 4
preparations available, 813t alkylating agents, 953–957 Chloasma, 734
second-generation, 802f, 803t, 804 antimetabolites, 957–961. See also Chloral hydrate, 382, 383f
third-generation, 802f, 803t, 804–805 Antimetabolites Chlorambucil, 953, 953f, 955t. See also
Cephamycin, 802, 804 antitumor antibiotics Alkylating agents
Cerebral insufficiency, senile, 295 anthracyclines, 962t, 964–965 Chloramphenicol, 822–823, 824t
Cerebral vasospasm, 205 bleomycin, 962t, 965–966 Chlordiazepoxide, 72, 385t, 393t. See also
Certolizumab mitomycin, 962t, 965 Benzodiazepines
description of, 993 brain cancer, 975 acute ethanol withdrawal treated with,
inflammatory bowel disease treated with, breast cancer 406t
1110–1112, 1111t stage I & II, 971 structure of, 382f
rheumatic disorders treated with, 654f, stage III & IV, 972 Chlorhexidine, 898t, 898–899
654–655 cell cycle kinetics and anti-cancer effect Chloride channel
Cestodes, 944–945. See also Anthelmintic in, 950f, 950–952 CFTR, 248b
drugs clinical pharmacology of, 969–975 in cystic fibrosis, 248b
Cetirizine, 281, 283, 283t, 296t. See also dermatologic GABA receptor complex versatility in,
H 1 -receptor antagonists alitretinoin, 1085 386, 387f, 388b
CETP inhibition, 638 bexarotene, 1085 Chloride channel activators
Cetrorelix, 678–679 romidepsin, 1085 irritable bowel syndrome treated with,
Cetuximab, 966t, 967, 992 vismodegib, 1085 1103
Cevimeline, 119, 122t vorinostat, 1085 laxatives, 1099
CFTR gene, 248b dosage factors in, 952 Chloride channel drugs
CFTR mutations, 248b drug combinations in, 951–952 arrhythmias treated with, 248
cGMP, 302, 302f drug resistance in, 952 preparations available, 251t
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Chagas disease fundamentals of, 969 Chloride (Cl ), 229–230, 230f
benznidazole for, 934 gastrointestinal cancers, 972–973 Chlorine, 899
nifurtimox for, 933t, 934–935 growth factor receptor inhibitors, 966t, 2-Chlorodeoxyadenosine (cladribine), 958t,
Chaparral, 1133t 967–969 961